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You are here: Published Weight Loss Studies > Drug Treatment Studies > Orlistat (Xenical)

Index of published clinical studies related to Orlistat (Xenical)

Research articles of clinical studies are listed by publication date, starting with the latest. Click on the title to view the abstract.

Well-designed clinical studies related to Orlistat (Xenical)

Comparison of orlistat and sibutramine in an obesity management program: efficacy, compliance, and weight regain after noncompliance. [2006 Dec]

Effect of weight loss with or without orlistat treatment on adipocytokines, inflammation, and oxidative markers in obese women. [2006 Oct-Dec]

Rise of plasma ghrelin with weight loss is not sustained during weight maintenance. [2006 Oct]

Evaluation of a primary care-oriented brief counselling intervention for obesity with and without orlistat. [2006 Oct]

Does metabolic syndrome mitigate weight loss in overweight Mexican American women treated for 1-year with orlistat and lifestyle modification? [2006 Mar]

Effect of multifactorial treatment on non-alcoholic fatty liver disease in metabolic syndrome: a randomised study. [2006 May]

Treatment of mild to moderate obesity with laparoscopic adjustable gastric banding or an intensive medical program: a randomized trial. [2006 May 02]

A double-blind randomized placebo-controlled trial of orlistat for the treatment of nonalcoholic fatty liver disease. [2006 May]

Randomized, double-blind, placebo-controlled trial of orlistat for weight loss in adolescents. [2006 Jan-Feb]

Orlistat in the treatment of overweight or obese Chinese patients with newly diagnosed Type 2 diabetes. [2005 Dec]

[Influence of orlistat therapy on serum insulin level and morphological and functional parameters of peripheral arterial circulation in obese patients] [2005 Nov]

Effect of orlistat, micronised fenofibrate and their combination on metabolic parameters in overweight and obese patients with the metabolic syndrome: the FenOrli study. [2005 Dec]

Effect of orlistat in obese patients with binge eating disorder. [2005 Oct]

X-PERT: weight reduction with orlistat in obese subjects receiving a mildly or moderately reduced-energy diet: early response to treatment predicts weight maintenance. [2005 Nov]

A comparison of meal replacements and medication in weight maintenance after weight loss. [2005 Oct]

The effects of loperamide on continence problems and anorectal function in obese subjects taking orlistat. [2005 Sep]

[Efficacy and safety of a short-time orlistat treatment in obese subjects] [2005 Apr-Jun]

Exercise training as an adjunct to orlistat therapy reduces oxidative stress in obese subjects. [2005 Aug]

Effect of orlistat on weight and body composition in obese adolescents: a randomized controlled trial. [2005 Jun 15]

Effect of Orlistat in obese patients with heart failure: a pilot study. [2005 May-Jun]

Cognitive behavioral therapy guided self-help and orlistat for the treatment of binge eating disorder: a randomized, double-blind, placebo-controlled trial. [2005 May 15]

A randomized study of orlistat in combination with a weight management programme in obese patients with Type 2 diabetes treated with metformin. [2005 May]

Effect of orlistat on postprandial lipemia, NMR lipoprotein subclass profiles and particle size. [2005 May]

Effect of orlistat on cardiovascular disease risk in obese adults. [2005 May]

Efficacy and safety comparative evaluation of orlistat and sibutramine treatment in hypertensive obese patients. [2005 Jan]

Efficacy of sibutramine, orlistat and combination therapy on short-term weight management in obese patients. [2004 Dec]

Comparison of metabolic effects of orlistat and sibutramine treatment in Type 2 diabetic obese patients. [2004 Aug]

Comparison of efficacy of sibutramine or orlistat versus their combination in obese women. [2004 May]

Lipid peroxides in obese patients and effects of weight loss with orlistat on lipid peroxides levels. [2005 Jan]

The ORLIstat and CArdiovascular risk profile in patients with metabolic syndrome and type 2 DIAbetes (ORLICARDIA) Study. [2004 Sep]

Addition of orlistat to conventional treatment in adolescents with severe obesity. [2004 Dec]

Orlistat as an adjunct therapy in type 2 obese diabetic patients treated with sulphonylurea: a Bangladesh experience. [2004 Apr]

A pilot study of orlistat treatment in obese, non-alcoholic steatohepatitis patients. [2004 Sep 15]

Effects of orlistat on obesity-related diseases - a six-month randomized trial. [2004 Sep]

What interventions should we add to weight reducing diets in adults with obesity? A systematic review of randomized controlled trials of adding drug therapy, exercise, behaviour therapy or combinations of these interventions. [2004 Aug]

Comparison of the effect of orlistat vs orlistat plus metformin on weight loss and insulin resistance in obese women. [2004 Aug]

Cholesterol lowering effect of dietary weight loss and orlistat treatment--efficacy and limitations. [2004 Jun 01]

Orlistat, sibutramine, or combination therapy: which performs better on waist circumference in relation with body mass index in obese patients? [2004 Mar]

Lipase inhibition by orlistat: effects on gall-bladder kinetics and cholecystokinin release in obesity. [2004 Mar 01]

The pathophysiology of faecal spotting in obese subjects during treatment with orlistat. [2004 Feb 01]

A systematic review of the clinical effectiveness of orlistat used for the management of obesity. [2004 Feb]

XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. [2004 Jan]

Effects of moderate weight loss and orlistat on insulin resistance, regional adiposity, and fatty acids in type 2 diabetes. [2004 Jan]

Effects of equal weight loss with orlistat and placebo on body fat and serum fatty acid composition and insulin resistance in obese women. [2004 Jan]

Lipase inhibition attenuates the acute inhibitory effects of oral fat on food intake in healthy subjects. [2003 Nov]

Weight loss in obese Mexican Americans treated for 1-year with orlistat and lifestyle modification. [2003 Dec]

Orlistat in hypertensive overweight/obese patients: results of a randomized clinical trial. [2003 Nov]

The effect of short-term (21-day) orlistat treatment on the physiologic balance of six selected macrominerals and microminerals in obese adolescents. [2003 Oct]

Randomized, double-blind, placebo-controlled comparison of the action of orlistat, fluvastatin, or both an anthropometric measurements, blood pressure, and lipid profile in obese patients with hypercholesterolemia prescribed a standardized diet. [2003 Apr]

Lowering of LDL cholesterol rather than moderate weight loss improves endothelium-dependent vasodilatation in obese women with previous gestational diabetes. [2003 Jun]

Weight reduction and long-term maintenance after 18 months treatment with orlistat for obesity. [2003 May]

Latin-American trial of orlistat for weight loss and improvement in glycaemic profile in obese diabetic patients. [2003 May]

Decreasing levels of tumour necrosis factor alpha and interleukin 6 during lowering of body mass index with orlistat or placebo in obese subjects with cardiovascular risk factors. [2003 May]

Effect of orlistat added to diet (30% of calories from fat) on plasma lipids, glucose, and insulin in obese patients with hypercholesterolemia. [2003 Apr 15]

Predictive value of early weight loss in obesity management with orlistat: an evidence-based assessment of prescribing guidelines. [2003 Jan]

[Info-congress. Prevention of type 2 diabetes in obese patients: first results with orlistat in the XENDOS study] [2002 Sep]

Acute effect of orlistat on post-prandial lipaemia and free fatty acids in overweight patients with Type 2 diabetes mellitus. [2002 Nov]

Orlistat improves blood pressure control in obese subjects with treated but inadequately controlled hypertension. [2002 Nov]

The effects of orlistat on body weight and glycaemic control in overweight patients with type 2 diabetes: a randomized, placebo-controlled trial. [2002 Nov]

Randomised trial of the effect of orlistat on body weight and cardiovascular disease risk profile in obese patients: UK Multimorbidity Study. [2002 Sep]

Orlistat for the treatment of obesity: rapid review and cost-effectiveness model. [2000 Oct]

Effect of orlistat in overweight and obese patients with type 2 diabetes treated with metformin. [2002 Jul]

Clinical efficacy of orlistat therapy in overweight and obese patients with insulin-treated type 2 diabetes: A 1-year randomized controlled trial. [2002 Jun]

Are soft tissue composition of bone and non-bone pixels in spinal bone mineral measurements by DXA similar? Impact of weight loss. [2002 Jan]

The cerebrospinal fluid/serum leptin ratio during pharmacological therapy for obesity. [2002 Apr]

Minor long-term changes in weight have beneficial effects on insulin sensitivity and beta-cell function in obese subjects. [2002 Jan]

Evaluation of the safety and efficacy of sibutramine, orlistat and metformin in the treatment of obesity. [2002 Jan]

The effects of orlistat on weight and on serum lipids in obese patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled, multicentre study. [2001 Nov]

Orlistat inhibits dietary cholesterol absorption. [2001 Oct]

Principles for enhanced recruitment of subjects in a large clinical trial. the XENDOS (XENical in the prevention of Diabetes in Obese Subjects) study experience. [2001 Oct]

Influence of orlistat on bone turnover and body composition. [2001 Aug]

Gastrointestinal side effects of orlistat may be prevented by concomitant prescription of natural fibers (psyllium mucilloid). [2001 Jul]

Orlistat maintains biliary lipid composition and hepatobiliary function in obese subjects undergoing moderate weight loss. [2001 Jun]

Weight change and blood coagulability and fibrinolysis in healthy obese women. [2001 Feb]

Comparative evaluation of fecal fat excretion induced by orlistat and chitosan. [2001 Jun]

Short-term orlistat treatment does not affect mineral balance and bone turnover in obese men. [2001 Jun]

Effect of orlistat-assisted weight loss in decreasing coronary heart disease risk in patients with syndrome X. [2001 Apr 01]

Effect of orlistat treatment on body composition and resting energy expenditure during a two-year weight-reduction programme in obese Finns. [2000 Dec]

Effects of sibutramine plus orlistat in obese women following 1 year of treatment by sibutramine alone: a placebo-controlled trial. [2000 Sep]

The effect of orlistat on body weight and coronary heart disease risk profile in obese patients: the Swedish Multimorbidity Study. [2000 Sep]

Fat intake and food choices during weight reduction with diet, behavioural modification and a lipase inhibitor. [2000 May]

Effects of weight loss with orlistat on glucose tolerance and progression to type 2 diabetes in obese adults. [2000 May 08]

One-year treatment of obesity: a randomized, double-blind, placebo-controlled, multicentre study of orlistat, a gastrointestinal lipase inhibitor. [2000 Mar]

Weight loss, weight maintenance, and improved cardiovascular risk factors after 2 years treatment with orlistat for obesity. European Orlistat Obesity Study Group. [2000 Jan]

Orlistat fails to alter postprandial plasma lipid excursions or plasma lipases in normal-weight male volunteers. [2000 Feb]

Orlistat in the long-term treatment of obesity in primary care settings. [2000 Feb]

Orlistat, a gastrointestinal lipase inhibitor, in therapy of obesity with concomitant hyperlipidemia. [1999 Sep-Oct]

The effect of orlistat on the fatty acid composition of serum lipid fractions in obese subjects. [1999 Sep]

Orlistat, a lipase inhibitor, for weight maintenance after conventional dieting: a 1-y study. [1999 Jun]

Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: a randomized controlled trial. [1999 Jan 20]

Treatment with orlistat reduces cardiovascular risk in obese patients. [1998 Dec]

[Reduction of obesity and improvement in metabolic parameters by inhibition of intestinal lipases: current results with orlistat] [1998]

Role of orlistat in the treatment of obese patients with type 2 diabetes. A 1-year randomized double-blind study. [1998 Aug]

Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. European Multicentre Orlistat Study Group. [1998 Jul 18]

Efficacy and tolerability of orlistat in the treatment of obesity: a 6-month dose-ranging study. Orlistat Dose-Ranging Study Group. [1998 Apr]

Insulin and leptin concentrations in obese humans during long-term weight loss. [1997 Sep]

A one-year trial to assess the value of orlistat in the management of obesity. [1997 Jun]

The effect of orlistat, an inhibitor of dietary fat absorption, on the absorption of vitamins A and E in healthy volunteers. [1996 Jul]

Lipase inhibition and hormonal status, body composition and gastrointestinal processing of a liquid high-fat mixed meal in moderately obese subjects. [1995 Nov]

Orlistat (Ro 18-0647), a lipase inhibitor, in the treatment of human obesity: a multiple dose study. [1995 Apr]


     
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