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Wieght loss & maintenance news: weight loss, diets, fitness, diet pills, weight-related diseases, bariatric surgery

We have compiled the list of news articles related to weight loss, diets, fitness, diet pills, weight-related diseases, bariatric surgery from online health/medical sources selected based on their reputation and reliability.

Obesity surgery triples among U.S. teens (AP)
Yahoo! News: Weight Loss News -- 2007-03-06

In a photo provided by his family, Erric Decker is shown in an undated photo prior to his gastric bypass surger in 2003 at the  age of 17. Decker was 5 feet, 8 inches tall and weighed 385 pounds. (AP Photo/The Decker Family)AP - The number of U.S. children having obesity surgery has tripled in recent years, surging at a pace that could mean more than 1,000 such operations this year, new research suggests. While the procedure is still far more common in adults, it appears to be slightly less risky in teens, according to an analysis of data on 12- to 19-year-olds who had obesity surgery from 1996 through 2003.


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More obese adolescents turning to surgery (Reuters)
Yahoo! News: Weight Loss News -- 2007-03-06
Reuters - In the current decade, there has been a dramatic increase in the number of obese adolescents having surgery to help them lose weight, although weight loss surgery remains an uncommonly performed procedure in young people....more >>

Weight-loss surgery triples for obese teens (Reuters)
Yahoo! News: Weight Loss News -- 2007-03-06

Undated file photo of obese person. The use of surgery to treat obesity has increased greatly among U.S. adolescents in recent years, with the number of operations tripling from 2000 to 2003, according to a study published on Monday. (file photo/Reuters)Reuters - The use of surgery to treat obesity has increased greatly among U.S. adolescents in recent years, with the number of operations tripling from 2000 to 2003, according to a study published on Monday.


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Walking More Likely In Neighborhoods With More 4-Way Intersections, RAND Study Finds
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-05
People are more likely to walk when they live in neighborhoods where there are more four-way intersections and a diverse mixture of businesses, according to a RAND Corporation study.A greater density of housing also may encourage walking, but only once density reaches a relatively high level, according to the RAND Health study that is one of the first to test whether urban design recommendations for creating walkable communities may help achieve their goal. [click link for full article]...more >>

Early Puberty In Girls Due to Being Overweight As A Toddler
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-05
US scientists have shown that being overweight as a toddler increases the chance that a girl will reach puberty early.The study from the University of Michigan's Mott Children's Hospital is published in the journal Pediatrics.Dr Joyce Lee, the lead author, and colleagues used the data on 354 girls from age 3 who were enrolled in the National Institute of Child Health and Human Development (NICHD) Study of Early Child Care and Youth Development (SECCYD). [click link for full article]...more >>

Staying Busy And Active Contributes To Longer Life
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-05
Physical activity as the elixir of youth might seem like old news, but there's a new twist, according to the March issue of Mayo Clinic Women's HealthSource. For the best chance of a long, healthy life, marathon training is not required. But, staying busy and active might be.Research published last year found that any activity that contributed to energy expenditure in older adults may help prolong life. [click link for full article]...more >>

Slimming World Voted Best Diet Aid
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-05
Slimming World proved such a success with online visitors to Review Centre during the last year that it easily won the best diet aid award for 2006, beating competition from 34 other well known diets and diet aids.The award is based on averages of ratings and user comments submitted by customers to Review Centre in 2006, and also for overall ratings and comments featured at the Review Centre site. [click link for full article]...more >>

Exercise, Diet, Supplements Play Role In Lowering Cholesterol Without Drugs
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-05
When it's time to rein in cholesterol, the go-to prescription is usually statins. These medications can reduce low-density lipoprotein (LDL) cholesterol -- the bad cholesterol -- from 25 percent to 50 percent. But for a variety of reasons, statins aren't an option for everyone.The March issue of Mayo Clinic Women's HealthSource outlines other ways to lower cholesterol levels. [click link for full article]...more >>

Obesity May Trigger Earlier Puberty for Girls (HealthDay)
Yahoo! News: Weight Loss News -- 2007-03-05
HealthDay - MONDAY, March 5 (HealthDay News) -- Childhood obesity may lead to earlier onset of puberty for girls, a U.S. study concludes....more >>

Obese woman unaware of pregnancy until near birth (Reuters)
Yahoo! News: Weight Loss News -- 2007-03-05
Reuters - A woman who weighs more than 400 pounds (180 kg) said on Sunday she did not know she was pregnant until two days before giving birth this week to a healthy baby boy....more >>

Childhood obesity triggers early puberty: study (Reuters)
Yahoo! News: Weight Loss News -- 2007-03-05

Children exercise at a swimming pool in Shanghai July 12, 2006. Childhood obesity in the United States appears to be causing girls to reach puberty at an earlier age, for reasons that are not clear, a study said on Monday. CHINA OUT (STRINGER/Reuters)Reuters - Childhood obesity in the United States appears to be causing girls to reach puberty at an earlier age, for reasons that are not clear, a study said on Monday.


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Asia-Pacific Has The Biggest Diabetes Burden In The World
Diabetes News From Medical News Today -- 2007-03-05
Given that in the year 2000 an estimated 83 million people in the Asia-Pacific region were living with type 2 diabetes, representing almost half of the 171 million people with diabetes worldwide, these findings highlight the huge impact that diabetes prevention and awareness campaigns could have in the area. In Australia alone, diabetes is responsible for 4,000 fatal heart attacks and strokes each year. [click link for full article]...more >>

SIR: 'Rapid Lysis' Dissolves Severe DVT
MedPage Today Endocrinology -- 2007-03-05
SEATTLE -- Combining thrombolytic medication with a clot removal device effectively dissolves extensive deep vein thrombosis (DVT) in a single session, according to a retrospective study....more >>

SIR: Partial and Complete Embolization of Uterine Fibroids Equally Effective
MedPage Today Endocrinology -- 2007-03-05
SEATTLE -- Cutting off blood flow to uterine fibroids alone by partial uterine arterial embolization appears to be as effective in treating fibroid symptoms as complete embolization of the uterine artery, according to a randomized study....more >>

SIR: Chemoembolization Unlikely to Injure Hepatic Artery
MedPage Today Endocrinology -- 2007-03-05
SEATTLE -- Chemoembolization for liver cancer may damage the hepatic artery but rarely enough to affect subsequent treatment, researchers said here....more >>

SIR: Radiofrequency Ablates Pain of Benign Bone Tumor
MedPage Today Endocrinology -- 2007-03-05
SEATTLE -- Radiofrequency ablation eliminates the debilitating bone pain of benign bone tumors without the risks associated with surgery, researchers here said....more >>

SIR: Stent-Graft Bests Surgery For Thoracic Aorta Repair
MedPage Today Endocrinology -- 2007-03-05
SEATTLE -- Endovascular repair of thoracic aortic aneurysms may carry substantially less risk of paraplegia and other poor outcomes than surgery, British researchers said here....more >>

CDEP: Lipid Spike Seen When Hormone Therapy Stops
MedPage Today Endocrinology -- 2007-03-05
ORLANDO, Fla. -- When post menopausal women stop hormone replacement therapy, LDL cholesterol levels are likely to spike, leading many physicians to prescribe statins that may be superfluous, according to researchers here....more >>

SIR: Percutaneous Cryoablation Freezes Out Kidney Tumors
MedPage Today Endocrinology -- 2007-03-05
SEATTLE -- For eliminating small kidney tumors, percutaneous cryoablation appears to be as effective as laparoscopic cryoablation, and about 60% cheaper, researchers reported here....more >>

Abdominal Obesity Is the Bane of Latin America
Medscape Diabetes Headlines -- 2007-03-05
Abdominal obesity seems to be the most important risk factor when it comes to MI in Latin America, a new analysis of the INTERHEART study has found.
Heartwire
Lisa Nainggolan...more >>

Change in Daylight Saving Time May Cause Medical Device Errors
Medscape Diabetes Headlines -- 2007-03-05
Medical systems that use date-time information for patient diagnosis and-or treatment could be affected.
Medscape Medical News
Yael Waknine...more >>

High-Fat Dairy Intake Reduces Risk for Anovulatory Infertility
Medscape Diabetes Headlines -- 2007-03-05
In a prospective study of healthy women, intake of high-fat dairy products was linked with a lower risk for anovulatory infertility; low-fat dairy foods increased the risk for this condition. (CME,CE)
Medscape Medical News...more >>

Dairy Calcium Intake Enhances Weight Loss in Overweight Diabetic Patients
Medscape Diabetes Headlines -- 2007-03-05
A study showed that high intake of calcium from low-fat dairy products enhanced weight loss in overweight patients with diabetes who were following isocaloric-restricted diets. (CME)
Medscape Medical News...more >>

Evolution of a Pulmonary Insulin Delivery System (Exubera) for Patients With Diabetes
Medscape Diabetes Headlines -- 2007-03-05
The findings highlighted in this Clinical Review suggest that this inhaled insulin device represents an important new development in the treatment of diabetes: It may improve glycemic control.
Medscape General Medicine...more >>

Pathohistological classification of pituitary tumors: 10 years of experience with the German Pituitary Tumor Registry
Endocrinology News -- 2007-03-05
European Journal of Endocrinology
Wolfgang Saeger, et al. – In 1996, the German Registry of Pituitary Tumors was founded by the Pituitary Section of the German Society of Endocrinology as a reference center for collection and consultant pathohistological studies of pituitary tumors. The experiences of the first 10 years of this registry based on 4122 cases will herein be reported. The data supplement former collections of the years 1970–1995 with 3480 surgically removed tumors or lesions of the pituitary region...more >>

Prevalent Rheumatoid Arthritis and Diabetes Among NHANES III Participants Aged 60 and Older
Endocrinology News -- 2007-03-05
Journal of Rheumatology
Julia F. Simard, et al. - Conclusion: While this study cannot definitively rule out a modest non-null association, we can conclude that there is no evidence of a strong cross-sectional association between prevalent RA and diabetes in subjects aged >= 60 years. Future longitudinal studies with more participants with RA are required to further evaluate a possible association between RA and the incidence of diabetes...more >>

Glycemic and Risk Factor Control in Type 1 Diabetes
Endocrinology News -- 2007-03-05
Diabetes Care
Eeg-Olofsson, K., et al. – Are recently updated treatment goals making a difference?<br>><b>Summary: </b> This study investigated the clinical characteristics of a large type 1 diabetic population and to evaluate the degree of fulfillment of recently updated treatment goals. A1C levels, treatment, and risk factors were analyzed in two cross-sectional samples of 9,424 patients in 1997 and 13,612 patients in 2004 and in a smaller longitudinal sample from 1997 to 2004. <br><b>Outcomes: </b>In this large cohort of type 1 diabetic patients, there was a slow improvement in glycemic and risk factor control from 1997 to 2004, although the gap between the clinical results and current Swedish and American treatment goals is still unsatisfactory. It is crucial that additional measures be taken to improve risk factor control in type 1 diabetic patients...more >>

Serum Zinc Level and Coronary Heart Disease Events in Patients With Type 2 Diabetes
Endocrinology News -- 2007-03-05
Diabetes Care
Soinio, M., et al. – Low serum zinc level a risk factor for CHD events in this diabetic population.<br>><b>Summary: </b> Serum zinc values were obtained from a group of 1,059 patients with type 2 diabetes, aged 45 - 64 years. Mean duration of diabetes was 8 years. CHD mortality and the incidence of nonfatal MI were assessed in a 7-year follow-up.<br><b>Outcomes: </b> Patients with a serum zinc concentration of lower 14.1 µmol/l at baseline had a higher risk for death from CHD than patients with serum zinc level above 14.1 µmol/l. The risks for fatal or nonfatal MI were 30.5 and 22.0%, respectively. A Cox regression analyses determined that low serum zinc concentration was significantly associated with CHD mortality and all CHD events even after adjustment for confounding variables...more >>

Prediction of Diabetic Nephropathy Using Urine Proteomic Profiling 10 Years Prior to Development of Nephropathy
Endocrinology News -- 2007-03-05
Diabetes Care
Hasan H. Otu, PHD., et al. – Is proteomic profiling valuable in identifying progression of diabetic nephropathy?<br>><b>Summary: </b> In a nested case-control study of Pima Indians with type 2 diabetes, baseline and 10-year urine samples were examined. Thirty one case subjects developed diabetic nephropathy over 10 years. The same number of control subjects were matched to case subjects according to diabetes duration, age, sex, and BMI but remained normoalbuminuric over the same 10 years. The study examined whether proteomic technologies could identify novel urine proteins associated with subsequent development of diabetic nephropathy.<br><b>Outcomes: </b>Urine proteomic profiling identifies normoalbuminuric subjects with type 2 diabetes who subsequently develop diabetic nephropathy. Further studies are needed to characterize the specific proteins involved in this early prediction...more >>

Superiority of Small Islets in Human Islet Transplantation
Endocrinology News -- 2007-03-05
Diabetes
Lehmann, R., et al. – Small islet size is a key factor in transplantation success.<br>><b>Summary: </b> This research assessed insulin secretion of large and small islets and quantified cell death during hypoxic conditions simulating the intraportal transplant environment. In the clinical setting, the influence of transplanted islet size on insulin production in patients with type 1 diabetes was analysed.<br><b>Outcomes: </b> Results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture. Islet size seems to be a key factor determining human islet transplantation outcome...more >>

Effect of Acute Exercise on AMPK Signaling in Skeletal Muscle of Subjects With Type 2 Diabetes
Endocrinology News -- 2007-03-05
Diabetes
Apiradee Sriwijitkamol, et al. – Activation of AMP-activated protein kinase (AMPK) by exercise induces several cellular processes in muscle. Exercise activation of AMPK is unaffected in lean (BMI 25 kg/m2) subjects with type 2 diabetes. However, most type 2 diabetic subjects are obese (BMI >30 kg/m2), and exercise stimulation of AMPK is blunted in obese rodents. We examined whether obese type 2 diabetic subjects have impaired exercise stimulation of AMPK, at different signaling levels, spanning from the upstream kinase, LKB1, to the putative AMPK targets...more >>

Prospective randomized controlled study of Hydrofiber® dressing containing ionic silver or calcium alginate dressings in non-ischaemic diabetic foot ulcer
Endocrinology News -- 2007-03-05
Diabetic Medicine
Jude, E. B, et al. – Are there measurable clinical effects of a primary wound dressing containing silver? <br>><b>Summary: </b> A prospective, multicentre study compared clinical efficacy and safety of AQUACEL® Hydrofiber® dressings containing ionic silver (AQAg) with those of Algosteril® calcium alginate (CA) dressings in managing out-patients with Type 1 or 2 diabetes mellitus and non-ischaemic Wagner Grade 1 or 2 DFUs. <br><b>Outcomes: </b> When added to standard care with appropriate off-loading, AQAg silver dressings were associated with favourable clinical outcomes compared with CA dressings, specifically in ulcer depth reduction and in infected ulcers requiring antibiotic treatment. This study reports the first significant clinical effects of a primary wound dressing containing silver on DFU healing...more >>

Thiazolidinediones and vascular damage
Endocrinology News -- 2007-03-05
Current Opinion in Endocrinology and Diabetes
Goldberg, Ronald B, - Will use of these drugs prevent cardiovascular disease?<br>><b>Summary: </b>The purpose of this review was to investigate the possibility of thiazolidinedione agents having vasculoprotective effects and if so whether these are associated with the prevention of cardiovascular disease.<br><b>Outcomes: </b>The weight of the experimental, subclinical and clinical assessments of the effects of these agents supports the contention that they are vasculoprotective. In the final analysis their use in clinical practice to prevent cardiovascular disease will mostly depend on whether clinical trials consistently demonstrate that they reduced cardiovascular events...more >>

Dipeptidyl peptidase-4 inhibitors and the management of type 2 diabetes mellitus
Endocrinology News -- 2007-03-05
Current Opinion in Endocrinology and Diabetes
Rosenstock, Julio, et al. – Long term studies needed to confirm potential of glycemic control.<br>><b>Summary: </b> The purpose of this research was to review recent clinical trials of oral dipeptidyl peptidase-4 inhibitors and examine their role in managing type 2 diabetes mellitus. <br><b>Outcomes: </b>Oral dipeptidyl peptidase-4 inhibitors may prove valuable in the treatment of diabetes, given their effectiveness in reducing glycated hemoglobin with neutral weight effects and without the adverse events associated with other agents. Dipeptidyl peptidase-4 inhibitors appear to improve islet function and may modify the course of diabetes; this, however, must be confirmed with long-term controlled studies to demonstrate sustained glycemic control that translates into [beta]-cell preservation...more >>

Increased extracellular signal regulated kinases phosphorylation in the adrenal gland in response to chronic ACTH treatment
Endocrinology News -- 2007-03-05
Journal of Endocrinology
Jorge G Ferreira, et al. - ACTH released from the pituitary acts through activation of cAMP/PKA in adrenocortical cells stimulating steroidogenesis. Although ACTH was originally thought to have anti-proliferative effects on the adrenal, recently it has been described that it could also have proliferative effects acting through other signalling cascades. This is also relevant in humans given the increased levels of ACTH occurring together with adrenal cortex hyperplasia observed in Cushing’s disease and possibly in other situations such as chronic stress...more >>

The Small Polyphenolic Molecule Kaempferol Increases Cellular Energy Expenditure and Thyroid Hormone Activation
Endocrinology News -- 2007-03-05
Diabetes
Wagner S. da-Silva, et al. – Disturbances in energy homeostasis can result in obesity and other metabolic diseases. Here we report a metabolic pathway present in normal human skeletal muscle myoblasts that is activated by the small polyphenolic molecule kaempferol (KPF). Treatment with KPF leads to an 30% increase in skeletal myocyte oxygen consumption...more >>

Insulin Secretion and Insulin Sensitivity in Relation to Fasting Glucose in Healthy Subjects
Endocrinology News -- 2007-03-05
Diabetes Care
Bo Ahrén, MD, PHD., - Does high, but still normal, fasting glucose contribute to augmented insulin secretion?<br>><b>Summary: </b> A total of 148 healthy 50+ year old women underwent a glucose-dependent arginine stimulation test and a 2-h euglycemic-hyperinsulinemic clamp. In the arginine test, arginine (5 g) was injected intravenously under baseline (fasting) conditions and after raising the glucose levels to 15 and >28 mmol/l. From this test, the acute insulin response (AIR) to arginine during the three glucose levels (AIR1, AIR2, and AIR3) were estimated.<br><b>Outcomes: </b> The researchers concluded that 1) raised fasting glucose augments baseline and maximal arginine-induced insulin secretion in healthy subjects, and 2) this is associated with reduced insulin sensitivity. This suggests that high, but still normal, fasting glucose may contribute to the augmented insulin secretion in subjects with low insulin sensitivity...more >>

Dual Endothelin Receptor Blockade Acutely Improves Insulin Sensitivity in Obese Patients With Insulin Resistance and Coronary Artery Disease
Endocrinology News -- 2007-03-05
Diabetes Care
Gunvor Ahlborg, MD, PHD., et al. – Endothelin (ET)-1 is a vasoconstrictor and proinflammatory peptide that may inhibit glucose uptake. The objective of the study was to investigate if ET (selective ETA and dual ETA+ETB) receptor blockade improves insulin sensitivity in patients with insulin resistance and coronary artery disease...Conclusion: Dual ETA+ETB receptor blockade acutely enhances insulin sensitivity in patients with insulin resistance and coronary artery disease, indicating an important role for endogenous ET-1...more >>

Prospective Study of Hyperglycemia and Cancer Risk
Endocrinology News -- 2007-03-05
Diabetes Care
Pär Stattin, MD, PHD., et al. – Is there an association between abnormal glucose metabolism and the development of cancer?<br>><b>Summary: </b> In the Västerbotten Intervention Project of northern Sweden, fasting and postload plasma glucose concentrations were available for 33,293 women and 31,304 men and 2,478 incident cases of cancer were identified. Relative risk (RR) of cancer for levels of fasting and postload glucose was calculated with the use of Poisson models, with adjustment for age, year of recruitment, fasting time, and smoking status. Repeated measurements 10 years after baseline in almost 10,000 subjects were used.<br><b>Outcomes: </b> Risk of cancer of the pancreas, endometrium, urinary tract, and of malignant melanoma was statistically significantly associated with high fasting glucose. The association of hyperglycemia with total cancer risk in women and in women and men combined for several cancer sites, independently of obesity, provides further evidence for an association between abnormal glucose metabolism and cancer...more >>

Effects of anethum graveolens and garlic on lipid profile in hyperlipidemic patients
Atherosclerosis/Lipids News -- 2007-03-05
Lipids in Health and Disease
Javad Kojuri, et al. – Hyperlipidemia as a major risk factor of atherosclerosis is treated with different drugs...Conclusion: Anethum has no significant effect on lipid profile, but garlic tablet has significant favorable effect on cholesterol, LDL-cholesterol, and HDL-cholesterol. Garlic may play an important role in therapy of hypercholesterolemia...more >>

Approximation of total visceral adipose tissue with a single magnetic resonance image
Atherosclerosis/Lipids News -- 2007-03-05
American Journal of Clinical Nutrition
Ellen W Demerath, et al. – A single axial image measured between the 4th and 5th lumbar vertebrae (L4-L5) is most frequently chosen to approximate total abdominal visceral adipose tissue (VAT) volume, but growing evidence suggests that this measurement site is not ideal...Conclusion: A single MR image located approximately at the L3 vertebra can accurately estimate total VAT volume in blacks and whites of both sexes...more >>

Dietary -linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects
Atherosclerosis/Lipids News -- 2007-03-05
American Journal of Clinical Nutrition
Guixiang Zhao, et al. – Atherosclerosis is a chronic inflammatory disease. We previously reported that a diet high in alpha linolenic acid (ALA) reduces lipid and inflammatory cardiovascular disease risk factors in hypercholesterolemic subjects...Conclusion: Increased intakes of dietary ALA elicit antiinflammatory effects by inhibiting IL-6, IL-1beta, and TNF-alpha production in cultured PBMCs. Changes in PBMC ALA and eicosapentaenoic acid (derived from dietary ALA) are associated with beneficial changes in TNF-alpha release...more >>

Increased Expression of Visfatin in Macrophages of Human Unstable Carotid and Coronary Atherosclerosis
Atherosclerosis/Lipids News -- 2007-03-05
Circulation
Tuva B. Dahl, MSc., et al. – Although the participation of inflammation in atherogenesis is widely recognized, the identification of the different components has not been clarified. In particular, the role of inflammation in plaque destabilization is not fully understood...Conclusion: Our findings suggest that visfatin should be regarded as an inflammatory mediator, localized to foam cell macrophages within unstable atherosclerotic lesions, that potentially plays a role in plaque destabilization...more >>

Endothelial-Specific Expression of Mitochondrial Thioredoxin Improves Endothelial Cell Function and Reduces Atherosclerotic Lesions
Atherosclerosis/Lipids News -- 2007-03-05
American Journal of Pathology
Haifeng Zhang, et al. - The function of the mitochondrial antioxidant system thioredoxin (Trx2) in vasculature is not understood. By using endothelial cell (EC)-specific transgenesis of the mitochondrial form of the thioredoxin gene in mice (Trx2 TG), we show the critical roles of Trx2 in regulating endothelium functions...more >>

Safety of Lovastatin/Extended Release Niacin Compared With Lovastatin Alone, Atorvastatin Alone, Pravastatin Alone, and Simvastatin Alone
Atherosclerosis/Lipids News -- 2007-03-05
American Journal of Cardiology
Alsheikh-Ali, Alawi A. MD., et al. – Are the label warnings about increased risk of adverse events with statin and niacin combinations valid?<br>><b>Summary: </b>A comparison review of the rate of adverse event reports (AERs) received by the United States Food and Drug Administration from 1999 to March 2005 associated with the combination of lovastatin/niacin-extended release (ER) with those of lovastatin or niacin-ER alone, and other commonly used statins.The prevalence of concomitant niacin-ER therapy in the statin-associated AERs was also calculated.<br><b>Outcomes: </b>The amount of serious AERs associated with the combination lovastatin/niacin-ER was similar to that of lovastatin or niacin-ER alone, and significantly less than that of atorvastatin or simvastatin used alone. The rates of liver and rhabdomyolysis AERs associated with lovastatin/niacin-ER were similar to those of the other statins or niacin-ER uses alone and lower than those associated with simvastatin alone. The incidence of niacin-ER use in statin-associated AERs was less than 1%. The findings indicate that statins can safely be used in combination as indicated in the national guidelines...more >>

Angiogenic Role of LYVE-1–Positive Macrophages in Adipose Tissue
Atherosclerosis/Lipids News -- 2007-03-05
Circulation Research
Chung-Hyun Cho, et al. – Here we report the discovery of a characteristic dense vascular network (DVN) in the tip portion of epididymal adipose tissue in adult mice. The DVN is formed by angiogenesis rather than by vasculogenesis, and has functional blood circulation. This DVN and its subsequent branching may provide a new functional route for adipogenesis...more >>

Complications Following Hip Replacement More Common In Obese Patients, Especially Women
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-04
Obese patients tend to have a higher prevalence of total hip replacements due to a higher incidence of hip osteoarthritis. This is of particular concern in light of the trend in rising rates of obesity in developed countries. A new study published in the March 2007 issue of [click link for full article]...more >>

Walkability Study Sheds Light Around Light Rail Stops In Portland & San Francisco Bay Area
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-04
Got a train to catch? The walk to the nearest stop has been put under scientific scrutiny, looking at distances involved and the environment along the way.The findings, which include the discovery that people often walk farther than they had thought despite their desire to minimize time and distance, are detailed in an award-winning paper by researchers at the University of Oregon and San Jose State University. A goal of the research - conducted in Portland, Ore. [click link for full article]...more >>

Excessive TV Viewing By Children Is Linked To Poor Eating Habits
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-04
The more a 3-year-old watches television, the more he or she consumes sugary drinks, and extra calories, Harvard researchers said at the American Heart Association's 47th Annual Conference on Cardiovascular Disease Epidemiology and Prevention."For every one-hour increase in TV viewing per day, we found higher intakes of sugar-sweetened beverages including juice (one extra serving per week) and total calories (46.3 more kcal/day)," said Sonia Miller, B.A. [click link for full article]...more >>

Schools Help Hold The Line Against Childhood Obesity, Study Says
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-04
Schools do more to help prevent obesity among children than they do to cause it, new research suggests.A nationwide study found that one measure of obesity rose more than twice as fast when kindergarten and first-grade students were on summer vacation than when they were in school.And obese children were helped most by being in school: they gained weight no faster than other children did during the school year. [click link for full article]...more >>

Simple Solutions To Postpartum Weight Retention
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-04
Women aiming to shed after pregnancy pounds should add daily walks and limit TV time and trans fats, according to a new study by Harvard researchers. "The childbearing years are a time of particular risk for weight gain in women," said lead author Emily Oken, M.D. "Modifiable behaviors in that early postpartum period such as diet, television viewing and walking can influence a woman's risk of retaining weight. [click link for full article]...more >>

Lipitor Significantly Reduced The Risk Of Serious Cardiovascular Events Compared With Simvastatin In An 80,000-Patient AnalysisManage
Cholesterol News From Medical News Today -- 2007-03-03
A retrospective analysis of a large U.S. managed care database showed that patients who took Pfizer's cholesterol-lowering medicine Lipitor(R) (atorvastatin calcium) Tablets had a significant 14 percent reduction in the risk of cardiovascular events, including heart attacks and strokes, compared with patients who took simvastatin. [click link for full article]...more >>

New Science-Based Guide To Natural Fat-Loss
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-02
American consumers have long been skeptical about weight-loss supplements, and rightly so. With dozens of nutrients, herbs, and food extracts being marketed as aids for weight loss, there is shockingly little reliable information available concerning the safety and efficacy of any given product. [click link for full article]...more >>

Diabetes Will Be A Bigger Burden Than Predicted, The Lancet
Diabetes News From Medical News Today -- 2007-03-02
WHO has predicted a 39% rise in the worldwideprevalence of diabetes between 2000 and 2030, butan Article in this week's Lancet indicates that this figuremight be a gross underestimation. Using populationbaseddata from Ontario, Lorraine Lipscombe andcolleagues have observed a 69% increase in theprevalence of known diabetes from 1995 to 2005; anincrease that already exceeds WHO's predicted rate. [click link for full article]...more >>

Study Confirms That Significant Insulin Dose Errors Can Result When Blood Glucose Meters Are Miscoded
Diabetes News From Medical News Today -- 2007-03-02
When persons with diabetes use miscoded blood glucose meters to determine how much insulin to take, significant errors in insulin dose can result that may potentially lead to short- and long-term health complications, according to findings of a new study just published in the Journal of Diabetes Science and Technology (http://www.journalofdst.org). [click link for full article]...more >>

'Mild' IVF Reduces Multiple Pregnancies
MedPage Today Endocrinology -- 2007-03-02
UTRECHT, The Netherlands -- IVF rates for term live births after "mild" ovarian stimulation with single-embryo transfer equaled the rates for standard stimulation with two-embryo transfer, Dutch researchers reported....more >>

Chronic Kidney Disease Prevalence Creeps Up
MedPage Today Endocrinology -- 2007-03-02
ATLANTA -- An estimated 16.8% of the U.S. population ages 20 and older has chronic kidney disease, reported researchers from the National Center for Chronic Disease Prevention and Health Promotion....more >>

No Additive Adrenal Suppression Seen With Intranasal Ciclesonide Added to Inhaled Fluticasone
Medscape Diabetes Headlines -- 2007-03-02
Patients with allergic rhinitis and asthma can take both drugs without increasing the risk for adrenal suppression.
Medscape Medical News
Paula Moyer...more >>

National Cholesterol Education Program - Adult Treatment Panel III, International Diabetes Federation, and WHO Definitions of the Metabolic Syndrome as Predictors of Cardiovascular Disease and Diabetes
Medscape Diabetes Headlines -- 2007-03-02
The authors found that the metabolic syndrome predicts diabetes beyond glucose intolerance alone.
Diabetes Care...more >>

Higher Dose of Vitamin D May Reduce Risk for Falls in Nursing Home Residents
Medscape Diabetes Headlines -- 2007-03-02
In a randomized study, nursing home residents in the highest vitamin D group (800 IU) had fewer fallers and a lower incidence rate of falls during 5 months than those taking lower doses. (CME,CE)
Medscape Medical News...more >>

Reaffirming the Public Good
Medscape Diabetes Headlines -- 2007-03-02
Darrell G. Kirch, MD, the new President of the AAMC in Washington, DC, urges us to collaboratively restore three of our most vital public goods: higher education, scientific research, and healthcare.
Medscape General Medicine...more >>

Author's Reply to "Reader's Response to 'Nuclear Mutagenesis'"
Medscape Diabetes Headlines -- 2007-03-02
Dr. Helen Caldicott's response to a reader on her WVE "Nuclear Mutagenesis."
Medscape General Medicine...more >>

Reader's Response to "Nuclear Mutagenesis"
Medscape Diabetes Headlines -- 2007-03-02
A reader responds to Dr. Helen Caldicott's WVE "Nuclear Mutagenesis."
Medscape General Medicine...more >>

Soaring Diabetes Rates Over Past 10 Years in Ontario Far Exceed WHO Projections
Medscape Diabetes Headlines -- 2007-03-02
Researchers say the nearly 70% increase in diabetes prevalence between 1995 and 2005 is due to both a spike in new cases and reduced diabetes mortality. Ethnicity of immigrants also explains part, but not all, of the dramatic increase.
Heartwire
Shelley Wood...more >>

The association between TSH within the reference range and serum lipid concentrations in a population-based study
Endocrinology News -- 2007-03-02
European Journal of Endocrinology
Asvold, B., et al. – Is there a significant link between TSH levels and lipid concentrations?<br>><b>Summary: </b> A cross-sectional, population-based study was carried out using 30,656 subjects without known thyroid disease. Using general linear models, mean concentrations of total serum cholesterol, low-density lipoprotein (LDL) cholesterol, non-high-density lipoprotein (HDL) cholesterol, HDL cholesterol and triglycerides across categories of TSH were calculated for each individual. <br><b>Outcomes: </b>Within the range of TSH that is considered clinically normal, it was found that increasing levels of TSH were associated with less favourable lipid concentrations. The association with serum lipids was linear across the entire reference range of TSH...more >>

Adipose Tissue as a Modulator of Clinical Inflammation: Does Obesity Reduce the Prevalence of Rheumatoid Arthritis?
Endocrinology News -- 2007-03-02
Journal of Rheumatology
Tamas Bartfai, et al. - Conclusion: Although both RA and obesity have been reported to be characterized by high serum levels of inflammatory cytokines, the frequency of one disorder was not increased in the other. We propose that the lack of association in prevalence between the 2 inflammatory states, rather than reflecting a post-hoc effect of the disease on BMI, is a function of the relative amounts of pro- and antiinflammatory mediators produced in adipose tissue, which under many circumstances leads to an overall systemic antiinflammatory tone...more >>

US adults average spending on diabetes treatment increases over 7 years
Endocrinology News -- 2007-03-02
Formulary
Between 1996 and 2003, average constant dollar expenditures on prescription medications by adults with >=1 medical event for the treatment of diabetes increased 87.3% in those aged 18 to 44 years, 114.9% in those aged 45 to 64 years, and 61.4% in those aged >=65 years...more >>

Growth hormone stimulates osteoprotegerin expression and secretion in human osteoblast-like cells
Endocrinology News -- 2007-03-02
Journal of Endocrinology
E Mrak, et al. – It is presently thought that osteoprotegerin (OPG) is a cytokine involved in the regulation of osteoblast/osteoclast crosstalk and maintenance of bone mass. Recent studies showed that GH replacement therapy in GH-deficient patients was able to induce a significant increase of OPG in the plasma, as well as in the cortical and the trabecular bone...more >>

Chronic testosterone treatment induces selective insulin resistance in subcutaneous adipocytes of women
Endocrinology News -- 2007-03-02
Journal of Endocrinology
Corbould, A., - Do androgens influence insulin-mediated glucose metabolism in adipose cells?<br>><b>Summary: </b>Preadipocytes harvested from s.c. adipose tissue of healthy women were differentiated in vitro, then treated with testosterone (T) and/or androgen receptor (AR) antagonists (cyproterone acetate, flutamide) for 48 hours. Maximal insulin-stimulated glucose uptake (insulin 10 nM) and increment following insulin stimulation were significantly impaired in cells treated with T 10 and 100 nmol/l.<br><b>Outcomes: </b> The findings of this study are relevant to understanding the pathogenesis of insulin resistance in hyperandrogenic women...more >>

Cholesteryl ester transfer protein and hyperalphalipoproteinemia in Caucasians
Atherosclerosis/Lipids News -- 2007-03-02
Journal of Lipid Research
Wim A. van der Steeg, et al. – It is unclear whether cholesteryl ester transfer protein (CETP) contributes to high density lipoprotein cholesterol (HDL-C) levels in hyperalphalipoproteinemia (HALP) in Caucasians. Moreover, even less is known about the effects of hereditary CETP deficiency in non-Japanese. We studied 95 unrelated Caucasian individuals with HALP. No correlations between CETP concentration or activity and HDL-C were identified...more >>

Consistently Stable or Decreased Body Mass Index in Young Adulthood and Longitudinal Changes in Metabolic Syndrome Components: The Coronary Artery Risk Development in Young Adults Study
Atherosclerosis/Lipids News -- 2007-03-02
Circulation
Lloyd-Jones, Donald M. MD, ScM., et al. – Is BMI the key to halting the the progression of metabolic syndrome risk factors with advancing age? <br>><b>Summary: </b>Prospective study of 1358 men and 1321 women ages 18 to 30 years enrolled in from 1985 to 1986, were stratified into groups by baseline BMI and change in BMI Patients were monitored for changes in metabolic syndrome components over 15 years. <br><b>Outcomes: </b>Over 15 years, participants whose BMI remained stable BMI had essentially unchanged levels of metabolic syndrome components, regardless of their baseline BMI, whereas those with an increased BMI had progressively worsening levels. The incidence of metabolic syndrome at year 15 was was lower at 2.2% in the stable BMI group versus 18.8% in the group whose BMI increased. The incidence of developing metabolic syndrome with advancing age can be decreased by maintaining a stable BMI over time...more >>

T-Cell Accumulation and Regulated on Activation, Normal T Cell Expressed and Secreted Upregulation in Adipose Tissue in Obesity
Atherosclerosis/Lipids News -- 2007-03-02
Circulation
Huaizhu Wu, MD., et al. – Obesity is associated with chronic inflammation, which includes increased macrophage accumulation in adipose tissue (AT) and upregulation of chemokines and cytokines...Conclusion: Obesity is associated with increased accumulation of T cells and macrophages in AT, which may play important roles in obesity-related disease by influencing preadipocyte/adipocyte functions...more >>

Relation of Osteoprotegerin to Coronary Calcium and Aortic Plaque
Atherosclerosis/Lipids News -- 2007-03-02
American Journal of Cardiology
Moeen Abedin MD., et al. – Circulating osteoprotegerin (OPG) has been shown to be elevated in patients with vascular disease. The role of OPG as a biomarker for atherosclerosis in a large, unselected population is not well known...Conclusion: Plasma OPG is independently associated with CAC and aortic plaque in an unselected population, suggesting it may be a novel biomarker for atherosclerosis in humans...more >>

Discontinuation of Lipid Modifying Drugs Among Commercially Insured United States Patients in Recent Clinical Practice
Atherosclerosis/Lipids News -- 2007-03-02
American Journal of Cardiology
Kamal-Bahl, Sachin J. PhD., et al. – Are lipid modifying drugs (LMD) being discontinued too soon in clinical practice? <br>><b>Summary: </b>Observational study using claims from the Ingenix Lab/Rx Database were used to identify patients aged ?20 years who were being treated with statins, extended-release niacin, fibrates, bile acid sequestrants, or ezetimibe from January 1, 2001, to June 30, 2003. The claims were reviewed to determine at which point treatment with the LMDs was discontinued <br><b>Outcomes: </b>Tne incidence of discontinuation after 1 year was 68.3% in patients treated with bile acid sequestrants, 55.4% with extended-release niacin users, 39.9% with fibrates, 33.0% with ezetimibe, and 28.9% with statins. There were high rates of discontiuations despite current knowledge about the benefits of long-term therapy...more >>

Calculation of arterial wall temperature in atherosclerotic arteries: Effect of pulsatile flow, arterial geometry, and plaque structure
Atherosclerosis/Lipids News -- 2007-03-02
BMC Medical Imaging
Obdulia Ley, et al. - Conclusions: The results indicate that direct temperature measurements should be taken (1) as close as possible to the plaque/lumen surface, as the calculations show a significant drop in temperature within 120 micrometers from the plaque surface; (2) in the presence of blood flow, temperature measurement should be performed in the downstream edge of the plaque, as it shows higher temperature independently of the arterial geometry; and (3) it is necessary to perform measurements at a sampling rate that is higher than the cardiac cycle...more >>

Paradoxical Changes in Muscle Gene Expression in Insulin-Resistant Subjects After Sustained Reduction in Plasma Free Fatty Acid Concentration
Atherosclerosis/Lipids News -- 2007-03-02
Diabetes
Mandeep Bajaj, et al. – Lipid oversupply plays a role in developing insulin resistance in skeletal muscle, decreasing expression of nuclear-encoded mitochondrial genes, and increasing extracellular matrix remodeling. To determine if a decrease in plasma lipid content reverses these abnormalities...more >>

Mitochondrial Dysfunction in Atherosclerosis
Atherosclerosis/Lipids News -- 2007-03-02
Circulation Research
Nageswara R. Madamanchi, et al. – Increased production of reactive oxygen species in mitochondria, accumulation of mitochondrial DNA damage, and progressive respiratory chain dysfunction are associated with atherosclerosis or cardiomyopathy in human investigations and animal models of oxidative stress...more >>

Characterization of the Natural Killer T-Cell Response in an Adoptive Transfer Model of Atherosclerosis
Atherosclerosis/Lipids News -- 2007-03-02
American Journal of Pathology
Paul A. VanderLaan, et al. - Natural killer T (NKT) cells have recently been implicated in atherogenesis, primarily for their ability to recognize and respond to lipid antigens. Because the atherosclerotic lesion is characterized by the retention and modification of lipids in the vascular wall, NKT cells may be involved in promoting the local vascular inflammatory response...more >>

The molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin
Atherosclerosis/Lipids News -- 2007-03-02
Journal of Lipid Research
Dawn E. Telford, et al. – The combination of ezetimibe, an inhibitor of Niemann-Pick C1-like 1 protein (NPC1L1), and an HMG-CoA reductase inhibitor decreases cholesterol absorption and synthesis. In clinical trials, ezetimibe plus simvastatin produces greater LDL-cholesterol reductions than does monotherapy. The molecular mechanism for this enhanced efficacy has not been defined...more >>

Usefulness Of Cardiovascular Disease Test Questioned
Cholesterol News From Medical News Today -- 2007-03-02
Researchers with Dartmouth Medical School and the Veterans Affairs Outcomes Group at the White River Junction (Vt.) VA Medical Center are questioning the usefulness of the C-Reactive Protein (CRP) test for guiding decisions about the use of cholesterol-lowering medication. [click link for full article]...more >>

Cholesterol In Stroke Patients Exceeds National Guidelines
Cholesterol News From Medical News Today -- 2007-03-02
Many stroke patients have cholesterol higher than national guidelines recommend that, if managed, may have prevented the stroke from happening, according to a study published in the February 27, 2007, issue of Neurology®, the scientific journal of the American Academy of Neurology. The study of 1,040 people hospitalized for stroke or transient ischemic attack (TIA) found that 27 percent had cholesterol higher than recommended by national guidelines. [click link for full article]...more >>

Exercise Reduces Risk Of Developing Invasive Breast Cancer, USC-Led Study Suggests
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-01
Significant findings have emerged from the California Teachers Study (CTS) that suggest long-term recreational physical activity plays a protective role against invasive and in situ breast cancer. [click link for full article]...more >>

Children Gain Weight Faster During Summer Vacation
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-01
Even though many schools fall short when it comes to offering daily physical education and balanced meals, children are more likely to pack on pounds during summer break than during the school year. A study based on twice-yearly body mass index (BMI) measurements from 5,380 children in 310 schools found that BMI gains were faster and more variable during summer vacation than during the kindergarten and first grade school years. [click link for full article]...more >>

New Blood Glucose Meters, Contour® And Breeze®2, Now Available In Pharmacies Nationwide, USA
Diabetes News From Medical News Today -- 2007-03-01
Bayer Diabetes Care, a division of Bayer HealthCare LLC and a member of the Bayer Group (NYSE: BAY), announced today the availability of the latest advances in their line of blood glucose meters: the new CONTOUR® and BREEZE®2 meters. As an innovator of meters with No Coding™ technology, Bayer's new meters now offer shorter testing times and easier functionality. [click link for full article]...more >>

Universal Health Care Surging in Popularity with Policy-makers: States Taking Lead
Medscape Diabetes Headlines -- 2007-03-01
Universal health care - - once dismissed by policy-makers - - has landed a starring role on the US policy agenda.
The Nation's health...more >>

Rimonabant: Endocannabinoid Inhibition for the Metabolic Syndrome
Medscape Diabetes Headlines -- 2007-03-01
Rimonabant, the first drug to target the endocannabinoid pathway, has major effects on both the metabolic syndrome and cardiovascular risk factor.
International journal of clinical practice...more >>

Fatty Liver and the Metabolic Syndrome
Medscape Diabetes Headlines -- 2007-03-01
Nonalcoholic fatty liver disease and its subset nonalcoholic steatohepatitis represent the liver manifestations of insulin resistance.
Current opinion in gastroenterology...more >>

Efficacy and Safety of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin Added to Ongoing Metformin Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Metformin Alone
Medscape Diabetes Headlines -- 2007-03-01
This study examines the efficacy and safety of oral sitagliptin added to ongoing metformin therapy.
Diabetes Care...more >>

Fatty acid metabolism in adipocytes: Functional analysis of fatty acid transport proteins 1 and 4
Atherosclerosis/Lipids News -- 2007-03-01
Journal of Lipid Research
Sandra Lobo, et al. – The role of fatty acid transport protein 1 (FATP1) and FATP4 in facilitating adipocyte fatty acid metabolism was investigated using stable FATP1 or FATP4 knockdown (kd) 3T3-L1 cell lines derived from retrovirus-delivered short hairpin RNA (shRNA). Decreased expression of FATP1 or FATP4 did not affect preadipocyte differentiation or the expression of FATP1...more >>

Seven Keys To Reduce Cholesterol - Free Special Report From Johns Hopkins Health Alerts
Cholesterol News From Medical News Today -- 2007-03-01
Johns Hopkins Health Alerts today released an important new Special Report, Seven Keys To Reduce Cholesterol, in order to reduce the risk of heart attack and improve one's overall health. The government's National Cholesterol Education Program (NCEP) estimates that at least 65 million Americans have high cholesterol levels that merit treatment with dietary and other lifestyle changes designed to lower cholesterol. [click link for full article]...more >>

Garlic Does Not Appear To Lower Cholesterol Levels
Cholesterol News From Medical News Today -- 2007-03-01
Three forms of garlic including raw garlic and two types of commercial garlic supplements did not significantly reduce low-density lipoprotein (LDL or "bad") cholesterol during a six-month trial, according to results published in the February 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. [click link for full article]...more >>

Magic Beans -- Anti-obesity Soya Could Help Prevent Diabetes
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-28
A diet rich in black soya beans could help control weight, lower fat and cholesterol levels, and aid in the prevention of diabetes, reports Lisa Richards in Chemistry & Industry, the magazine of the SCI.Yellow soya has already been hailed for its cholesterol lowering capabilities; this is one of the reasons why frozen food manufacturer Birds Eye has added the beans to its range. [click link for full article]...more >>

Hip-Surgery Complications More Common in Obese Women: Study (HealthDay)
Yahoo! News: Weight Loss News -- 2007-02-28
HealthDay - WEDNESDAY, Feb. 28 (HealthDay News) -- Obese people, especially women, are more likely to suffer complications following hip replacement surgery, Swiss researchers say....more >>

Patients With Type 1 Diabetes Don't Wake In Response To Hypoglycemia
Diabetes News From Medical News Today -- 2007-02-28
A study of 16 patients with type 1 diabetes mellitus (T1DM) and 16 normal individuals shows that only one of the 16 T1DM patients, as compared to ten healthy control participants, awakened upon hypoglycemia.Bernd Schultes and colleagues from the University of Lubeck induced hypoglycemia with insulin under controlled conditions and then assessed sleep with polysomography. A fall in plasma glucose to 2. [click link for full article]...more >>

Growth Hormone To Boost Athletic Performance Risks Diabetes
Diabetes News From Medical News Today -- 2007-02-28
Use of growth hormone to boost athletic performance can lead to diabetes, reports a study published ahead of print in the British Journal of Sports Medicine.The study reports the case of a 36 year old professional body-builder who required emergency care for chest pain.He had lost 40 kg in 12 months, during which he had also experienced excessive urination, thirst, and appetite. [click link for full article]...more >>

Glucose Intolerance Linked To Cancer Risk In Women
Diabetes News From Medical News Today -- 2007-02-28
High blood glucose levels -- even before they reach the level needed for a diagnosis of diabetes -- may signal an increased risk for cancer in women, according to a new study being published in the March issue of Diabetes Care. The March journal also includes a study that found a link between high levels of persistent organic pollutants (POPs) in a person's bloodstream and insulin resistance, a precursor for type 2 diabetes. [click link for full article]...more >>

Ice Cream and Whole-Fat Milk Smooth the Way to Conception
MedPage Today Endocrinology -- 2007-02-28
BOSTON -- Eating rich ice cream and drinking whole-fat milk, and using heavy cream for coffee, may help reward women shooting for pregnancy, researchers here reported. ...more >>

Non-Alcoholic Fatty Liver Disease: Natural History, Pathogenesis and Treatment
Medscape Diabetes Headlines -- 2007-02-28
Non-alcoholic fatty liver disease is used to describe the alcohol-like liver injury that occurs in the absence of alcohol abuse, and the predominant risk factor appears to be insulin resistance.
The British Journal of Diabetes and Vascular Disease...more >>

Effect of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin as Monotherapy on Glycemic Control in Patients With Type 2 Diabetes
Medscape Diabetes Headlines -- 2007-02-28
This study examines the efficacy and safety of once-daily oral sitagliptin as monotherapy in patients with type 2 diabetes.
Diabetes Care...more >>

Conference Report: The International Diabetes Federation 19th World Diabetes Congress, Cape Town, South Africa
Medscape Diabetes Headlines -- 2007-02-28
The third issue of this special report focuses on A Diabetes Outcome Progression Trial and other studies presented at the International Diabetes Federation World Congress. (CME)
Medscape Diabetes & Endocrinology
Pesach Segal...more >>

Journal Scan - Type 2 Diabetes
Medscape Diabetes Headlines -- 2007-02-28
The third issue of this special report focuses on A Diabetes Outcome Progression Trial and other studies presented at the International Diabetes Federation World Congress. (CME)
Medscape Diabetes & Endocrinology
Gregory Nichols...more >>

Expert Column - A Diabetes Outcome Progression Trial (ADOPT)
Medscape Diabetes Headlines -- 2007-02-28
The third issue of this special report focuses on A Diabetes Outcome Progression Trial and other studies presented at the International Diabetes Federation World Congress. (CME)
Medscape Diabetes & Endocrinology
Steven Haffner...more >>

Call for Papers
Medscape Diabetes Headlines -- 2007-02-28
Submit your paper to Medscape's MEDLINE-PUBMED-indexed medical journal, Medscape General Medicine.
Medscape Family Medicine...more >>

Healthcare Systems and Motivation
Medscape Diabetes Headlines -- 2007-02-28
The author discusses the historic roots of the US healthcare "system" and the self- and other-directed motivations of physicians.
Medscape General Medicine...more >>

Pay, Pride, and Public Purpose: Why America's Doctors Should Support Universal Healthcare
Medscape Diabetes Headlines -- 2007-02-28
The authors defend 3 reasons why it is in a physician's own self-interest to support universal healthcare.
Medscape General Medicine...more >>

Novel Drug Significantly Reduces Visceral Fat in HIV-Infected Patients
Medscape Diabetes Headlines -- 2007-02-28
In a phase 3 trial, TH9507, a novel analog drug to stimulate natural growth hormone, reduced visceral fat by 20% at 6 months.
Medscape Medical News...more >>

Type 2 Diabetes: The Latest Research, Volume 3
Medscape Diabetes Headlines -- 2007-02-28
The third issue of this special report focuses on A Diabetes Outcome Progression Trial and other studies presented at the International Diabetes Federation World Congress. (CME)...more >>

Scheduling Of Orlistat - National Drugs And Poisons Schedule Committee, Australia
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-27
The National Drugs and Poisons Schedule Committee (NDPSC) reconsidered the scheduling and advertising status of orlistat (contained in the medicine Xenical) at its February 2007 meeting. After reviewing a large number of submissions from consumer, industry and professional bodies, the NDPSC has decided that orlistat should be retained in Schedule 3 as a Pharmacist Only medicine. [click link for full article]...more >>

Chain Restaurants Encourage Americans To Over Eat Says Watchdog
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-27
A US watchdog has charged chain restaurants with encouraging Americans to over eat. It is not unusual to find a single meal packing in more than several days' worth of calories says the US Center for Science in the Public Interest (CSPI).CSPI are calling for all chain restaurants to show nutritional information, including the calorie value of each dish, in their menus. [click link for full article]...more >>

Long-Term Safety Data Show The LAP-BAND(R) Adjustable Gastric Banding System Results In Fewer Complications Compared To Gastric Bypass
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-27
Researchers from Legacy Good Samaritan Obesity Institute announced today the results from a 5-year study of the safety of laparoscopic adjustable gastric banding (LAGB) compared to laparoscopic Roux-en Y gastric bypass (LRYGB), two bariatric surgical procedures performed in the United States for the treatment of morbid obesity. All patients undergoing LAGB received the LAP-BAND(R) System, which is the only FDA-approved adjustable implant device for individualized weight loss. [click link for full article]...more >>

Obese British boy to stay with family (Reuters)
Yahoo! News: Weight Loss News -- 2007-02-27
Reuters - British social workers decided on Tuesday to allow an eight-year-old boy who weighs almost 200 pounds (91 kg) to remain at home with his mother, who has refused to stop feeding him junk food....more >>

Obese British eight-year-old can stay with family (AFP)
Yahoo! News: Weight Loss News -- 2007-02-27

Connor McCreaddie(R), an eight-year-old British boy who weighs 14 stone (90Kg, 200Lbs), and his mother Nicola McKeown, pose in front of their house in North Shields. McCreaddie will be allowed to stay with his mother after social workers decided against taking him into care.(AFP/Str )AFP - An eight-year-old British boy who weighs 14 stone (90 kilograms) will be allowed to stay with his mother after social workers decided against taking him into care Tuesday.


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UK childcare workers may remove obese boy from home (Reuters)
Yahoo! News: Weight Loss News -- 2007-02-27

Connor McCreaddie (L), eight, and his mother Nicola McKeown pose for photographers outside their home in Wallsend, northern England February 26, 2007. British social workers decided on Tuesday to allow an eight-year-old boy who weighs almost 200 lb (90 kg) to remain at home with his mother, even though she has refused to stop feeding him junk food. (Nigel Roddis/Reuters)Reuters - British social workers will meet an eight-year-old boy who weighs almost 200 pounds (91 kg) on Tuesday to decide whether he should be taken away from his mother after she refused to stop feeding him junk food.


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PKC-Epsilon Links Fat To Insulin Resistance
Diabetes News From Medical News Today -- 2007-02-27
The accumulation of fat in the liver (hepatic steatosis) can result in non-alcoholic fatty liver disease, which is associated with hepatic insulin resistance and type 2 diabetes mellitus. However, the mechanisms by which fat accumulation leads to hepatic insulin resistance have not been well characterized. [click link for full article]...more >>

One Step Closer To A Potential Cure For Diabetes
Diabetes News From Medical News Today -- 2007-02-27
For the millions of people worldwide who are afflicted with diabetes, we are now one step closer to a potential cure for the disease.Spring Point Project, a non-profit organization created to expedite the widespread availability of islet tissue for diabetes care, has now conducted the first animal population of its biosecure animal facility in Western Wisconsin to breed and maintain high-health, pathogen-free pigs. [click link for full article]...more >>

Scholl's Armstrong In Spain Keynote: 'Amputations Worse Than Cancer'
Diabetes News From Medical News Today -- 2007-02-27
The Spanish National Symposium on the Diabetic Foot last week was the scene for a keynote address that delivered a strong message proposing "a marriage of technology with common sense for the next decade." The address was delivered by David G. Armstrong, DPM, PhD, Professor of Surgery and Associate Dean at Scholl College at Rosalind Franklin University. [click link for full article]...more >>

Debate Continues Over Utility of Metabolic Syndrome
Medscape Diabetes Headlines -- 2007-02-27
While the diagnosis has been accepted by some as a useful predictor of cardiovascular disease and diabetes, others say that more robust measures should be used.
Medscape Medical News...more >>

FDA Approvals: RPM, HumaPen Memoir-Luxura HD, Gateway
Medscape Diabetes Headlines -- 2007-02-27
The FDA has approved an attachment for a respiratory gating system (RPM), insulin pens with digital memory capability (HumaPen Memoir and Luxura), and a thoracolumbar plate system (Gateway).
Medscape Medical News
Yael Waknine...more >>

Garlic Does Not Lower Cholesterol Say Researchers
Cholesterol News From Medical News Today -- 2007-02-27
A new US research study shows that garlic does not lower cholesterol, contrary to popular belief.The study is published in the Archives of Internal Medicine.The scientists, led by Dr Christopher Gardner at the Stanford Prevention Research Center, California, tested raw garlic and two well known garlic supplements in adults with moderately elevated levels of LDL or "bad" cholesterol. [click link for full article]...more >>

LifeCycle Pharma Announces Positive Data From LCP-AtorFen Phase I Clinical Program
Cholesterol News From Medical News Today -- 2007-02-27
LifeCycle Pharma A/S (OMX: LCP) announced today positive results from the company's Phase I clinical program with LCP-AtorFen, a fixed-dose combination product of atorvastatin and fenofibrate for the treatment of high cholesterol levels. The program was a comparative pharmacokinetic study between LCP-AtorFen and Lipitor(R) and Tricor(R) and was carried out in Canada. LCP-AtorFen has a convenient single pill once-daily dosing regime and is without food effect. [click link for full article]...more >>

Heavily Obese Eight Year Old Boy Could Go Into Care As Last Resort
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-26
An eight-year old boy who weighs 14 stone (196 lbs or 88.9 kilos) could be put into care by his local health authority as a last resort to help him lose weight.Connor McCreaddie, who lives with his mother in Wallsend, North Tyneside, UK is four time as heavy as he should be for his age. An intensive exercise programme and some diet changes have helped him come down by a stone and half (21 lbs, 9. [click link for full article]...more >>

Mother may lose custody of obese boy (AP)
Yahoo! News: Weight Loss News -- 2007-02-26

Connor McCreaddie right aged 8 who weighs  218 pounds (99 kilograms)  and his mother Nicola McKeown, left, outside their home in Wallsend, 300 miles (480 kilometers) north of London, England, Monday Feb. 26, 2007. Connor who weighs more than three times the average for his age, could be taken into protective custody  away from his mother for his own benefit.  An unnamed health official was quoted as telling a newspaper that the family had repeatedly failed to attend appointments with nurses, nutritionists and social workers.(AP Photo/Scott Heppell)AP - Authorities are considering taking an 8-year-old boy who weighs 218 pounds into protective custody unless his mother improves his diet, officials said Monday.


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Protein Linked To Elevated BMI In People Of American Indian And Mexican Ancestry Discovered By U Of M
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-25
University of Minnesota researchers have discovered a variant of a common blood protein, apolipoprotein C1, in people of American Indian and Mexican ancestry that is linked to elevated body mass index (BMI), obesity and Type 2 diabetes.The finding were published in the International Journal of Obesity. [click link for full article]...more >>

GlaxoSmithKline Acquires Exclusive Rights To Over-the-counter Orlistat For Markets Outside The US From Roche Group
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-25
GlaxoSmithKline plc (GSK) announced today that it has acquired from Roche Group exclusive rights to the weight-loss medicine, orlistat, for over-the-counter (OTC) use in markets outside the US, excluding Japan. GSK anticipates filing orlistat for OTC approval in Europe and certain key international markets by the end of 2007. [click link for full article]...more >>

New Device Safeguards Against Medication Errors At Home
Diabetes News From Medical News Today -- 2007-02-25
Patients suffering from chronic illness such as diabetes, congestive heart failure, coronary artery disease, and depression, can take six-to-nine different medications a day - oftentimes more. Skipped doses, misinterpretation or labels, or confusion over what pills to take at what time can be fatal. [click link for full article]...more >>

New Storage Instructions Approved For BYETTA®
Diabetes News From Medical News Today -- 2007-02-25
Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN) and Eli Lilly and Company (NYSE: LLY) announced today that the U.S. Food and Drug Administration (FDA) has approved more convenient patient storage instructions for BYETTA® (exenatide) injection. BYETTA Pens can now be kept at a room temperature not to exceed 77 degrees F (25 degrees C) after first use.With the updated label, refrigeration of BYETTA is no longer required after first use. [click link for full article]...more >>

Lilly Introduces World's First Digital Insulin Pen With Memory
Diabetes News From Medical News Today -- 2007-02-25
Eli Lilly and Company today announced the launch of the first insulin pen with memory, HumaPen® MEMOIR™, to help simplify the daily management of diabetes.MEMOIR is designed to meet the needs of people with diabetes who take several shots of mealtime insulin each day. [click link for full article]...more >>

Building A Better Breakfast To Manage Weight
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-24
Breakfast alone may not be the solution to reducing obesity among American consumers, but some reformulation of morning selections could prove beneficial in the battle against the bulge according to the latest issue of Food Technology. [click link for full article]...more >>

Role Of Cholesterol In Alzheimer's Disease Unclear, Reports The 'Harvard Men's Health Watch'
Cholesterol News From Medical News Today -- 2007-02-24
It sounds simple: The lower your cholesterol, the better your heart health. But a man's heart and his head don't always agree. In fact, the relationships among cholesterol levels, psychological function, and neurologic disorders are complex and sometimes controversial, reports the March 2007 issue of Harvard Men's Health Watch. There are two major forms of dementia: vascular dementia and Alzheimer's disease. [click link for full article]...more >>

Childhood Weight Linked To Proximity To Green Space And Food Stores
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-23
Living in greener neighborhoods or in closer proximity to grocery stores is associated with reduced risk of being overweight, according to a study of more than 7,000 children ages 3 to 18 conducted by researchers from the Indiana University School of Medicine; the Department of Geography, Indiana University-Purdue University Indianapolis; and the University of Cincinnati. The study, the largest of its type to date, appears in the March/April issue of the [click link for full article]...more >>

Diabetes Risk Factors Develop Earlier In Women Than Men
Diabetes News From Medical News Today -- 2007-02-23
The "diabetes clock" may start ticking in women years in advance of a medical diagnosis of the disease, new research has shown.Epidemiologists at the University at Buffalo have found that newly identified risk factors for diabetes found in the blood, such as markers of endothelial dysfunction, chronic sub-acute inflammation and blood clotting factors, are present early on in women who eventually progress from normal glucose status to the pre-diabetic condition. [click link for full article]...more >>

Research Identifies Risk-Factor Genes For Type 2 Diabetes
Diabetes News From Medical News Today -- 2007-02-23
A new study led by researchers at the McGill University Health Centre (MUHC) has identified four genes that increase the risk of developing type 2 diabetes. This form of diabetes is the most common worldwide and affects nearly 2 million Canadians. In recent years, the prevalence of Type 2 diabetes has increased rapidly. This genetic discovery may help stem this rise.This genetic study, published in the journal Nature, was led by MUHC endocrinologist Dr. [click link for full article]...more >>

CureDM, Inc. Achieves Two Drug Discovery Milestones
Diabetes News From Medical News Today -- 2007-02-23
CureDM, Inc., a biopharmaceutical company working to develop new therapies that prevent, ameliorate, or reverse diabetes, announces its achievement of two preclinical drug discovery milestones. "Meeting these milestones represents significant progress for CureDM," said Loraine V. [click link for full article]...more >>

Manhattan Pharmaceuticals Completes Enrollment In Phase 2a Study Of Oral Oleoyl-estrone For Obesity
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-22
Manhattan Pharmaceuticals, Inc. (Amex: MHA) today announced it completed patient enrollment in its first Phase 2a multi-center, international clinical study evaluating the safety and preliminary efficacy of oral Oleoyl-estrone (OE) for the treatment of obesity. This randomized, double-blind, placebo-controlled, parallel group study enrolled 100 patients at two clinical trial sites in the US and one in Europe. [click link for full article]...more >>

High-Dose Vitamin D Cuts Nursing Home Residents' Falls
MedPage Today Endocrinology -- 2007-02-22
BOSTON -- Nursing home residents taking 800 IU of vitamin D were less likely to fall and had a 72% decrease in falls compared with those taking a placebo, according to a five-month study....more >>

Prediabetes Gives Women Head Start on Heart and Diabetes Risk
MedPage Today Endocrinology -- 2007-02-22
BUFFALO, N.Y. -- The countdown to diabetes and coronary heart disease may start earlier for women with prediabetes than for men, researchers said here....more >>

Programmed For Obesity
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-21
Obesity is generally discussed in terms of caloric intake (how much a person eats) and energy output (how much a person exercises). However, according to a University of Missouri-Columbia scientist, environmental chemicals found in everyday plastics and pesticides also may influence obesity. [click link for full article]...more >>

Rewarding Fat Rats
Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-21
We all remember a time when we were paralyzed in the face of a tough decision. For animals in the natural world, making the right choice can mean the difference between life and death.When rats and other animals choose the thing that leads to a "reward," such as food, changes happen in the body and the brain. Describing and understanding those changes has been the focus of Natural Sciences and Engineering Research Council (NSERC) grantee Peter Shizgal for most of his career. [click link for full article]...more >>

New DVD game battles childhood obesity (AP)
Yahoo! News: Weight Loss News -- 2007-02-21
AP - Obesity may be a global epidemic, but it's Obeez City that is spreading out of control in a new DVD game....more >>

Kids Living Near 'Green Spaces' Less Likely to Be Overweight (HealthDay)
Yahoo! News: Weight Loss News -- 2007-02-21
HealthDay - WEDNESDAY, Feb. 21 (HealthDay News) -- Children who live in densely populated urban areas may be less likely to be overweight if they have parks and lawns in their neighborhoods, a U.S. study suggests....more >>

Blood Pressure Heads Down In The Absence Of PPAR-gamma
Diabetes News From Medical News Today -- 2007-02-21
One of the most serious health conditions in the developed world is the metabolic syndrome (MetS), a collection of disorders (such as obesity and insulin resistance) that lead to increased risk of developing type 2 diabetes and heart disease. A protein known as PPAR-gamma has been shown to be affect most aspects of MetS. However, these studies have had to focus on the affects of PPAR-gamma on one aspect of MetS at a time because mice lacking PPAR-gamma in all cells die before birth. [click link for full article]...more >>

New Storage Instructions Approved For BYETTA(R)
Diabetes News From Medical News Today -- 2007-02-21
Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN) and Eli Lilly and Company (NYSE: LLY) announced today that the U.S. Food and Drug Administration (FDA) has approved more convenient patient storage instructions for BYETTA(R) (exenatide) injection. BYETTA Pens can now be kept at a room temperature not to exceed 77 degrees F (25 degrees C) after first use. With the updated label, refrigeration of BYETTA is no longer required after first use. [click link for full article]...more >>

Pregnancy Hormone Repairs MS-type Neural Damage
MedPage Today Endocrinology -- 2007-02-21
CALGARY, Alberta -- A pregnancy hormone may offer a key to halting or reversing the progression of multiple sclerosis and other demyelinating diseases, researchers here reported....more >>

Rosiglitazone (Avandia) Linked to Fractures in Women
MedPage Today Endocrinology -- 2007-02-21
ROCKVILLE, Md. -- The FDA informed physicians today of a report by GlaxoSmithKline of an increased number of arm, hand, and foot fractures among women taking rosiglitazone (Avandia) for newly diagnosed type 2 diabetes....more >>

rosiglitazone, Avandia
MedicineNet Diabetes General -- 2007-02-21
Title: rosiglitazone, Avandia
Category: Medications
Created: 11/28/1999 6:13:00 PM
Last Editorial Review: 2/21/2007...more >>

Some 600 Thai schools ban soft drinks to fight obesity (AFP)
Yahoo! News: Weight Loss News -- 2007-02-20

An elephant distributes toys to Thai schoolchildren in December 2006. Some 600 primary schools across Thailand have vowed to ban sugary drinks from the playground and classroom in an effort to curb soaring child obesity rates in the kingdom.(AFP/File/Pornchai Kittiwongsakul)AFP - Some 600 primary schools across Thailand have vowed to ban sugary drinks from the playground and classroom in an effort to curb soaring child obesity rates in the kingdom.


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Study Of Diabetes And Race Reveals The Imperfect Science Of Defining Ethnic Groups
Diabetes News From Medical News Today -- 2007-02-20
While previous biomedical research studies have found that genetics and race increase risk for some diseases, a new look into how researchers study genetic triggers of type 2 diabetes suggests that defining race remains an inexact science, with social and historic facts mixing with biology throughout the research process. [click link for full article]...more >>

SCCM: Risks OF Tight Glucose Control In ICU Outweigh Benefits
MedPage Today Endocrinology -- 2007-02-20
ORLANDO -- The risks of tight glycemic control for patients in intensive care outweigh the benefits, a Belgian researcher said here....more >>

Healthy Women With High Cholesterol At Increased Risk Of Stroke
Cholesterol News From Medical News Today -- 2007-02-20
Healthy women with no history of heart disease or stroke significantly increase their chances of having a stroke if they have high cholesterol, according to a study of more than 27,000 women published in the February 20, 2007, issue of Neurology®, the scientific journal of the American Academy of Neurology. [click link for full article]...more >>

Primitive Yeast Yields Secrets Of Human Cholesterol And Drug Metabolism
Cholesterol News From Medical News Today -- 2007-02-20
By first probing the way primitive yeast make cholesterol, a team of scientists has discovered a long-sought protein whose human counterpart controls cholesterol production and potentially drug metabolism.The collaborative study by investigators at Johns Hopkins University School of Medicine, Vanderbilt University, Indiana University and Eli Lilly Co., was published in the February issue of Cell Metabolism. [click link for full article]...more >>

Elucidation Of The Genome For Diabetics With DNA Chips
Diabetes News From Medical News Today -- 2007-02-19
The genome of patients with type 2 diabetes (DT2) has been elucidated, for the first time, thanks to the use of new DNA chip technologies allowing 400,000 DNA mutations to be studied simultaneously. New genes conferring a predisposition to DT2 have been identified. They include the zinc transporter of pancreatic insulin-secreting cells (ZnT8), which is a potential target for treatment. [click link for full article]...more >>

Cholesterol Linked With Type 2 Diabetes
Diabetes News From Medical News Today -- 2007-02-19
An international team of scientists have discovered a possible link between accumulation of cholesterol and type 2 diabetes.The study was based at Canada's Vancouver Child and Family Research Institute at the University of British Columbia, and is published online in Nature Medicine.Type 2 diabetes is defined by two things. One is insulin resistance, and the other is reduced insulin production. [click link for full article]...more >>

Culturally Specific Diabetes Management Helps Low-Income Patients
Diabetes News From Medical News Today -- 2007-02-19
Diabetes case management that takes a patient's specific culture into consideration can help increase life expectancy and decrease the incidence of diabetes-related complications over the patient's lifetime, a new study finds."Better management results in reduced long-term complications, such as blindness, stroke, amputation and nerve damage," said lead researcher Todd Gilmer, Ph.D. [click link for full article]...more >>

Novartis, The Broad Institute, And Lund University Announce Release Of Genome-wide Analysis Of Genes Associated With Type 2 Diabetes
Diabetes News From Medical News Today -- 2007-02-18
Novartis, The Broad Institute, and Lund University today announced the completion of a genome-wide map of genetic differences in humans and their relationship to type 2 diabetes and other metabolic disorders. All results of the analysis are being made accessible, free of charge on the internet to scientists around the world. [click link for full article]...more >>

FDA Accepts Two Supplemental New Drug Applications To Expand The U.S. Labeling For JANUVIA™
Diabetes News From Medical News Today -- 2007-02-18
Merck & Co., Inc. today announced that the U.S. Food and Drug Administration (FDA) has accepted for standard review two supplemental New Drug Applications (sNDAs) for JANUVIA™ (sitagliptin), and the Company expects FDA action on both sNDAs by mid-October.One sNDA is filed in support of a proposed new indication for the use of JANUVIA, as an adjunct to diet and exercise, in combination with metformin as initial therapy to improve glycemic control. [click link for full article]...more >>

Impaired breathing in obese tied to big waist (Reuters)
Yahoo! News: Weight Loss News -- 2007-02-16

A passenger waits for a delayed flight at Heathrow airport's terminal four in London August 12, 2006. Morbidly obese men tend to have more breathing difficulties than morbidly obese women, partly because they have much larger waistlines, a new study suggests. (Toby Melville/Reuters)Reuters - Morbidly obese men tend to have more breathing difficulties than morbidly obese women, partly because they have much larger waistlines, a new study suggests.


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CDC Report Provides First State-Specific Data On Persons Living With Heart Disease
Cholesterol News From Medical News Today -- 2007-02-16
The Centers for Disease Control and Prevention (CDC) today released a report that finds a wide range of variation in the prevalence of coronary heart disease (a narrowing of the arteries that feed the heart), heart attack and angina (chest pain that occurs when the heart does not get enough blood). The report provides the first ever information on the percentage of people living with heart disease in all 50 states and U.S. territories. [click link for full article]...more >>

New Version Of Devices To Treat Clogged Neck Arteries Approved By U.S. Food And Drug Administration
Cholesterol News From Medical News Today -- 2007-02-16
The Cordis Endovascular Division of Cordis Corporation, today announced U.S. Food and Drug Administration (FDA) approval to market its PRECISE(R) RX Nitinol Self-Expanding Stent and ANGIOGUARD(R) RX Emboli Capture Guidewire System to treat clogged neck arteries. Approval of the Cordis carotid system was announced today at the Arizona Heart Institute's International Congress on Endovascular Interventions in Scottsdale, Arizona. [click link for full article]...more >>

U.S. offers drugmakers advice on obesity drugs (Reuters)
Yahoo! News: Weight Loss News -- 2007-02-15
Reuters - As more Americans struggle with growing waistlines, U.S. health officials on Wednesday set out their own tips for drugmakers seeking to develop products for people trying to shed pounds....more >>

High carb diet not linked to colon cancer (Reuters)
Yahoo! News: Weight Loss News -- 2007-02-14
Reuters - Eating large amounts of carbohydrates does not appear to increase the risk of colon cancer in women, according to study findings published in the American Journal of Epidemiology....more >>

Experts Devise New Women's Heart Risk Predictor (HealthDay)
Yahoo! Health: Cholesterol News -- 2007-02-14
Women may soon have a better idea of what their actual cardiovascular disease risk is for the next 10 years and beyond....more >>

Articles In The New England Journal Of Medicine Confirm On-Label, Long-Term Safety And Efficacy Of The CYPHER(R) Sirolimus-Eluting Coronary Stent
Cholesterol News From Medical News Today -- 2007-02-13
The long-term safety of the CYPHER(R) Sirolimus-eluting Coronary Stent, specifically in terms of death, myocardial infarction (heart attacks) and stent thrombosis (also known as blood clots), is comparable to that of bare metal stents when used according to product labeling, according to a variety of studies appearing today in the New England Journal of Medicine (NEJM). [click link for full article]...more >>

FDA Grants Priority Review To Lovenox® (Enoxaparin Sodium Injection) Supplemental New Drug Application (sNDA) For Additional Type Of Heart Attack
Cholesterol News From Medical News Today -- 2007-02-12
Sanofi-aventis announced today the Food and Drug Administration (FDA) has accepted for review a supplemental new drug application (sNDA) for the anticoagulant Lovenox® (enoxaparin sodium injection) for the treatment of patients with acute ST-segment elevation myocardial infarction (STEMI), a type of acute heart attack. STEMI is a heart attack in which an artery is generally completely blocked for sufficient time to cause heart muscle damage. [click link for full article]...more >>

Obesity exacts heavy price in Saudi Arabia (AFP)
Yahoo! News: Weight Loss News -- 2007-02-10

Women walk outside a shopping mall in Riyadh. Almost one in five Saudis suffer from obesity, costing the country more than three billion dollars a year, a top medical official said in remarks published.(AFP/File/Bilal Qabalan)AFP - Almost one in five Saudis suffer from obesity, costing the country more than three billion dollars a year, a top medical official said in remarks published.


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Better Control of Diabetes Could Reduce Stroke (HealthDay)
Yahoo! Health: Cholesterol News -- 2007-02-08
Spanish ID: 601775 --> ...more >>

Study Sees Benefits in Boosting Levels of 'Good' Cholesterol (HealthDay)
Yahoo! Health: Cholesterol News -- 2007-02-07
Scientists have shown for the first time that raising "good" cholesterol levels is almost as important as lowering levels of "bad" cholesterol in reducing heart-threatening plaque in arteries....more >>

Gene Variant May Predict Heart Disease, Stroke (HealthDay)
Yahoo! Health: Cholesterol News -- 2007-02-03
Researchers have identified a gene variant associated with the early signs of heart disease and stroke in women....more >>

Reversal Of Early VCJD Symptoms May One Day Be Possible
Cholesterol News From Medical News Today -- 2007-02-02
UK scientists have shown that symptoms of prion disease in mice similar to vCJD in humans can be reversed if treated early enough. The study is published in the journal Neuron.The biggest problem with getting the treatment to work on humans will be the early diagnosis of vCJD before it does permanent damage to the brain. Currently the only sure way to diagnose vCJD in the early stages is to take a sample of brain tissue, a dangerous procedure. [click link for full article]...more >>

U.S. Kids' Health Habits Put Them at Risk (HealthDay)
Yahoo! Health: Cholesterol News -- 2007-01-27
Spanish ID: 601375 --> ...more >>

Metabolic Syndrome Predicts Heart Risk: Study (HealthDay)
Yahoo! Health: Cholesterol News -- 2007-01-24
A cluster of cardiac factors known as "metabolic syndrome" is a strong indicator of increased risk of heart disease, an exhaustive review of the literature concludes....more >>

Mom's Stem Cells Might Treat Child's Diabetes
MedicineNet Diabetes General -- 2007-01-23
Title: Mom's Stem Cells Might Treat Child's Diabetes
Category: Health News
Created: 1/23/2007 2:06:00 AM
Last Editorial Review: 1/23/2007 2:06:04 AM...more >>

HDL Is The New Frontier For Beating Heart Disease
Cholesterol News From Medical News Today -- 2007-01-23
Most people fixate on the wrong number in the cholesterol equation for reducing the risk of cardiovascular disease (CVD). It actually may be more important to know if your good HDL cholesterol is too low ( [click link for full article]...more >>

Academy Honors 18 For Major Contributions To Science
Cholesterol News From Medical News Today -- 2007-01-22
The National Academy of Sciences (NAS) will honor 18 individuals with awards recognizing extraordinary scientific achievements in the areas of astronomy, biology, medicine, chemistry, geology, oceanography, physics, and psychology. [click link for full article]...more >>

Some Blood Pressure Drugs Boost Diabetes Risk (HealthDay)
Yahoo! Health: Cholesterol News -- 2007-01-19
Some common blood pressure drugs can substantially increase the risk of diabetes, especially among those already at risk for the condition, U.S. researchers report....more >>

A New Fat Replacement For Trans Fat Raises Blood Sugar In Humans, Study Shows
Cholesterol News From Medical News Today -- 2007-01-19
Last month, New York City outlawed the use of partially hydrogenated oils, known as trans fats, in restaurants, a ban now under consideration in other cities, including Boston and Chicago. But novel research conducted in Malaysia and at Brandeis University shows that a new method of modifying fat in commercial products to replace unhealthy trans fats raises blood glucose and depresses insulin in humans, common precursors to diabetes. [click link for full article]...more >>

Not So Strange Bedfellows: Menopause And High Cholesterol
Cholesterol News From Medical News Today -- 2007-01-14
Not So Strange Bedfellows: Menopause and High Cholesterol: Denise Janosik, M.D., associate professor of internal medicine at Saint Louis University School of Medicine, warns that women entering menopause have something else to worry about: increasing cholesterol levels. "Studies have shown that as women age, bad cholesterol levels rise," she says. [click link for full article]...more >>

Low-Income Minorities at Risk for Peripheral Artery Disease (HealthDay)
Yahoo! Health: Cholesterol News -- 2007-01-13
Spanish ID: 600985 --> ...more >>

Oral Insulin May Be One Step Closer
MedicineNet Diabetes General -- 2007-01-11
Title: Oral Insulin May Be One Step Closer
Category: Health News
Created: 1/11/2007
Last Editorial Review: 1/11/2007...more >>

Experimental Drug Tackles Inherited High Cholesterol (HealthDay)
Yahoo! Health: Cholesterol News -- 2007-01-11
A new drug that helps people with a severe, inherited form of high cholesterol looks promising, a study found....more >>

Penn Researchers Demonstrate Ability Of New Therapy To Treat Patients With Severely Elevated Cholesterol Levels
Cholesterol News From Medical News Today -- 2007-01-11
Researchers at the University of Pennsylvania School of Medicine have demonstrated the potential of a new type of therapy for patients who suffer from high cholesterol levels. The findings are in the January 11 issue of the New England Journal of Medicine (NEJM). In this study, patients with homozygous familial hypercholesterolemia (FH), a high-risk condition refractory to conventional therapy, had a remarkable 51% reduction in low-density lipoprotein (LDL) or "bad cholesterol" levels. [click link for full article]...more >>

Published Study Shows Benefits Of Diachrome For People With Type 2 Diabetes
Cholesterol News From Medical News Today -- 2007-01-10
Nutrition 21, Inc. (NASDAQ: NXXI) has announced the results of a recent placebo controlled, double-blind, randomized, single center study that demonstrated that Diachrome®, a patented combination of chromium picolinate and biotin, safely improves blood glucose levels and cholesterol metabolism in people with type 2 diabetes. [click link for full article]...more >>

Stop Sitting And Start! Walking
Cholesterol News From Medical News Today -- 2007-01-10
WHAT: Did you know that walking for as little as 30 minutes a day provides heart health benefits for life? In fact, regular brisk walking can lower both bad cholesterol (LDL) levels and high blood pressure, help overweight individuals achieve and maintain weight loss and reduce their risk of stroke. Walking is accessible, free and has the lowest dropout rate of any kind of exercise. [click link for full article]...more >>

Girls Most Likely to Gain Weight as Pre-Teens (HealthDay)
Yahoo! Health: Cholesterol News -- 2007-01-09
Spanish ID: 600804 --> ...more >>

Arthritis Roller Coaster
MedicineNet Diabetes General -- 2007-01-05
Title: Arthritis Roller Coaster
Category: Doctor's Views
Created: 5/15/2000 10:21:00 AM
Last Editorial Review: 1/5/2007...more >>

How To Trap Heart Attack-Inducing Lipoproteins In The Blood
Cholesterol News From Medical News Today -- 2007-01-05
Atherosclerosis is a disease of the blood vessels that causes many problems, including heart attacks. It is caused by a buildup of fat (lipid)-containing macrophages (the rubbish-collecting cells of the immune system) in the arteries. The presence in the blood of high levels of remnant lipoproteins, cholesterol-rich particles that are produced as the large lipoprotein complexes that transport lipids around the body are degraded, potently promotes the development of atherosclerosis. [click link for full article]...more >>

Mouse Study Reveals Diabetes Secrets
MedicineNet Diabetes General -- 2007-01-04
Title: Mouse Study Reveals Diabetes Secrets
Category: Health News
Created: 1/4/2007 2:06:00 AM
Last Editorial Review: 1/4/2007 2:05:50 AM...more >>

Health Tip: What's an A1c Test?
MedicineNet Diabetes General -- 2006-12-08
Title: Health Tip: What's an A1c Test?
Category: Health News
Created: 12/8/2006 2:06:00 AM
Last Editorial Review: 12/8/2006 2:05:32 AM...more >>

Obesity Boosts Kidney Risk in Type 1 Diabetes
MedicineNet Diabetes General -- 2006-12-07
Title: Obesity Boosts Kidney Risk in Type 1 Diabetes
Category: Health News
Created: 12/7/2006 2:06:00 AM
Last Editorial Review: 12/7/2006 2:05:32 AM...more >>

New Diabetes Drug Improves Blood Sugar, Weight Loss
MedicineNet Diabetes General -- 2006-12-06
Title: New Diabetes Drug Improves Blood Sugar, Weight Loss
Category: Health News
Created: 12/6/2006 2:06:00 AM
Last Editorial Review: 12/6/2006 2:05:31 AM...more >>

New Type 2 Diabetes Drug Delays Disease Progression
MedicineNet Diabetes General -- 2006-12-05
Title: New Type 2 Diabetes Drug Delays Disease Progression
Category: Health News
Created: 12/5/2006 2:06:00 AM
Last Editorial Review: 12/5/2006 2:05:30 AM...more >>

Diabetes
MedicineNet Diabetes General -- 2006-12-05
Title: Diabetes
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 12/5/2006...more >>

Diabetes Treatment
MedicineNet Diabetes General -- 2006-12-05
Title: Diabetes Treatment
Category: Diseases and Conditions
Created: 12/5/2006
Last Editorial Review: 12/5/2006...more >>

Diabetes Drug Halts Weight Gain in Kids Taking Antipsychotics
MedicineNet Diabetes General -- 2006-12-04
Title: Diabetes Drug Halts Weight Gain in Kids Taking Antipsychotics
Category: Health News
Created: 12/2/2006 2:05:00 AM
Last Editorial Review: 12/4/2006...more >>

Extreme Exercise Can Slow the Heart
MedicineNet Weight Management General -- 2006-08-03
Title: Extreme Exercise Can Slow the Heart
Category: Health News
Created: 8/3/2006 1:57:00 AM
Last Editorial Review: 8/3/2006 1:56:52 AM...more >>

Late-Night Snacks May Reset Body Clock
MedicineNet Weight Management General -- 2006-08-02
Title: Late-Night Snacks May Reset Body Clock
Category: Health News
Created: 8/2/2006
Last Editorial Review: 8/2/2006...more >>

Obesity Vaccine Looks Promising
MedicineNet Weight Management General -- 2006-08-01
Title: Obesity Vaccine Looks Promising
Category: Health News
Created: 8/1/2006 1:57:00 AM
Last Editorial Review: 8/1/2006 1:56:54 AM...more >>

TV Watching Lowers Physical Activity: Study
MedicineNet Weight Management General -- 2006-08-01
Title: TV Watching Lowers Physical Activity: Study
Category: Health News
Created: 8/1/2006 1:57:00 AM
Last Editorial Review: 8/1/2006 1:56:53 AM...more >>

Chondromalacia Patellae (Patellofemoral Syndrome)
MedicineNet Weight Management General -- 2006-08-01
Title: Chondromalacia Patellae (Patellofemoral Syndrome)
Category: Diseases and Conditions
Created: 8/6/1998
Last Editorial Review: 8/1/2006...more >>

Summer Sports Without the Sprains
MedicineNet Weight Management General -- 2006-07-30
Title: Summer Sports Without the Sprains
Category: Health News
Created: 7/30/2006 1:57:00 AM
Last Editorial Review: 7/30/2006 1:56:53 AM...more >>

Diet and Exercise: The Real Fountains of Youth
MedicineNet Weight Management General -- 2006-07-29
Title: Diet and Exercise: The Real Fountains of Youth
Category: Health News
Created: 7/29/2006 1:57:00 AM
Last Editorial Review: 7/29/2006 1:56:55 AM...more >>

Weightlifting Can Tear the Heart
MedicineNet Weight Management General -- 2006-07-28
Title: Weightlifting Can Tear the Heart
Category: Health News
Created: 7/28/2006 1:57:00 AM
Last Editorial Review: 7/28/2006 1:56:55 AM...more >>

Osteoarthritis
MedicineNet Weight Management General -- 2006-07-28
Title: Osteoarthritis
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 7/28/2006...more >>

Obesity: Tougher on Women's Health?
MedicineNet Weight Management General -- 2006-07-28
Title: Obesity: Tougher on Women's Health?
Category: Health News
Created: 7/28/2006
Last Editorial Review: 7/28/2006...more >>

Welcome to the E-Exercise Revolution
MedicineNet Weight Management General -- 2006-07-27
Title: Welcome to the E-Exercise Revolution
Category: Health News
Created: 7/27/2006 1:57:00 AM
Last Editorial Review: 7/27/2006 1:56:56 AM...more >>

'Sweet Tooth' Types Drawn to Fruit
MedicineNet Weight Management General -- 2006-07-27
Title: 'Sweet Tooth' Types Drawn to Fruit
Category: Health News
Created: 7/27/2006 1:57:00 AM
Last Editorial Review: 7/27/2006 1:56:55 AM...more >>

World Briefing | Europe: Britain: Officials May Take Custody Of Extremely Overweight Boy
NYT > Weight
Social services authorities in Britain are considering taking 8-year-old Connor McCreaddie, who weighs 218 pounds, into protective custody unless his mother, Nicola McKeown, improves his diet; photo (S)... ...more >>

[TS] You Want Some Truth With That?
NYT > Weight
Editorial says fast-food restaurant chains should comply with New York City's new regulation that they list calories alongside menu prices; says city, with little or no state or federal help, has taken necessary step in face of widespread obesity and disease... ...more >>

PERSONAL HEALTH; Out of Control: A True Story of Binge Eating
NYT > Weight
Binge eating is the most common eating disorder but is still not considered a formal diagnosis....more >>

GEAR TEST WITH Joy Bauer, Dietitian; Keeping Tabs on Your Fat
NYT > Weight
Joy Bauer, dietitian, tests scales with built-in body-fat monitors....more >>

[TS] Army Giving More Waivers In Recruiting
NYT > Weight
The number of waivers granted to recruits with criminal backgrounds has grown about 65 percent over 3 years....more >>

[TS] COLLEGES; Female Athletes Embrace Size, Spurring a Debate Over Weight
NYT > Weight
Weights of male athletes are widely publicized by college teams but issue of weighing female athletes is subject of vigorous debate; some colleges, like Duke, weigh basketball players regularly to guard against rapid weight gain or loss, but others do not weigh at all; longtime coach Jody Conradt points to sensitivity about eating disorders among 'Type A' personalities; female athletes also face same societal pressures as other women to be thin and possess body type that is often unrealistic, especially for sports; eating-disorder specialist Dr Ron A Thompson says NCAA recommends against regular weigh-ins; opposes 'public degradation' of lining athletes up for weighing; policies at Oklahoma and Texas explained; Oklahoma center Courtney Paris, one of leading scorers and rebounders, discusses her large size as issue, conceding she has to work at being in condition; photo (M)... ...more >>

FASHION DIARY; Looking Beyond the Runway for Answers on Underweight Models
NYT > Weight
This is far from the first time that models have been singled out, and moralized about, as potentially unhealthy and somehow inherently bad....more >>

REALLY?
NYT > Weight
Quick weight gain may be among the birth-control pill’ s most dreaded side effects but how much does it really add to your waistline?...more >>

ECONOMIX; What's a Pound Of Prevention Really Worth?
NYT > Weight
Preventive medicine just doesn’ t pay in the current American medical system....more >>

[TS] Body Mass and the Student Body
NYT > Weight
Editorial criticizes program in Arkansas and other states that measures students' body mass index and sends home 'obesity report cards'; says schools should serve healthier foods and focus on physical education instead of demoralizing students with fat label... ...more >>

National Briefing | Science And Health: Weight Adds To Girls' Heart Disease Risk
NYT > Weight
Growth and Health Study conducted by National Heart, Lung and Blood Institute says girls as young as 9 who are overweight are more likely than girls of regular weight to develop serious short-term and long-term health problems that increase their risk of developing heart disease (S)... ...more >>

As Obesity Fight Hits Cafeteria, Many Fear a Note From School
NYT > Weight
Growing number of schools around nation are reporting students' body mass scores to parents as tactic in war on childhood obesity, while serving cake and pizza in cafeteria and cutting down on physical education; even health authorities who support distributing students's scores worry about such inconsistent messages, saying they could result in eating disorders and social stigma, misinterpretation of numbers that experts say are confusing, and sense of helplessness about high scores; in north-central Pennsylvania school district of farms and factories, more than quarter of students have scores in 95th percentile or higher, meaning they are officially overweight; among those in highest percentile is homecoming queen at high school; many parents voice outrage or shock at getting letter telling them how much their children should weigh; photos (M)... ...more >>

China Tightens Adoption Rules For Foreigners
NYT > Weight
China reportedly will tighten rules on foreign adoptions, ruling out adoptive parents who are single, obese, older than 50 or who fail to meet certain financial, physical or psychological standards; responds to enormous spike in applications that far exceeds number of available babies, mostly girls; plan raises anxiety among Americans for whom China is leading source of foreign-born adopted children; government's aim now is control number of applications and give children best chance to be raised by healthy, stable parents; applicants will have to have body-mass index under 40, no criminal record, high school diploma and be free of certain health problems like cancer and AIDS; couples have to be married at least two years, have no more than two divorces between them and have income of at least $10,000 per person in household; American agency officials and adoptive parents comment; photo (M)... ...more >>

World Briefing | Europe: Italy: Milan Bans Too-Thin Models
NYT > Weight
Milan formally bars too-thin models ahead of its major fashion show in February; says it bans models with body mass index of less than 18.5; photo (S)... ...more >>

I Heard It Through the Diet Grapevine
NYT > Weight
While popular diets and fasts come and go, “ master cleanse” remains a perennial favorite....more >>

Five new facts could change our understanding of starvation
The Doctors Lounge - Endocrinology and Diabetes
In an article published in The Lancet, Rainer Gross, PhD, UNICEF's chief of nutrition discusses five facts about world hunger....more >>

Heart complications of hyperthyroidism restricted to AF
The Doctors Lounge - Endocrinology and Diabetes
Neither hypo- or hyperthyroidism is associated with a higher risk for other cardiovascular problems....more >>

ACTOS shows significant benefits for diabetics
The Doctors Lounge - Endocrinology and Diabetes
A study shows that ACTOS reduces the risk of cardiovascular events by an extra 16% on top of standard medication....more >>

Canadian study demonstrates new approach to achieving diabetes control
The Doctors Lounge - Endocrinology and Diabetes
The INSIGHT study demonstrates early addition of insulin glargine therapy safely achieved better glycemic than adding oral agents....more >>

Ruboxistaurin (RBX) may reduce risk of vision loss in diabetics
The Doctors Lounge - Endocrinology and Diabetes
Phase III trial demonstrates ruboxistaurin (RBX) may reduce the risk of vision loss especially in diabetic macular edema....more >>


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