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Wieght loss & maintenance news: weight loss, diets, fitness, diet pills, weight-related diseases, bariatric surgery
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We have compiled the list of news articles related to weight loss, diets, fitness, diet pills, weight-related diseases, bariatric surgery from online health/medical sources selected based on their reputation and reliability.
| Obesity surgery triples among U.S. teens
(AP)
| | Yahoo! News: Weight Loss News -- 2007-03-06 |  AP - The number of U.S. children having obesity surgery has tripled in recent years, surging at a pace that could mean more than 1,000 such operations this year, new research suggests. While the procedure is still far more common in adults, it appears to be slightly less risky in teens, according to an analysis of data on 12- to 19-year-olds who had obesity surgery from 1996 through 2003.
...more >> |
| More obese adolescents turning to surgery
(Reuters)
| | Yahoo! News: Weight Loss News -- 2007-03-06 | | Reuters - In the current decade, there
has been a dramatic increase in the number of obese adolescents
having surgery to help them lose weight, although weight loss
surgery remains an uncommonly performed procedure in young
people....more >> |
| Weight-loss surgery triples for obese teens
(Reuters)
| | Yahoo! News: Weight Loss News -- 2007-03-06 |  Reuters - The use of surgery to treat obesity
has increased greatly among U.S. adolescents in recent years,
with the number of operations tripling from 2000 to 2003,
according to a study published on Monday.
...more >> |
| Walking More Likely In Neighborhoods With More 4-Way Intersections, RAND Study Finds | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-05 | | People are more likely to walk when they live in neighborhoods where there are more four-way intersections and a diverse mixture of businesses, according to a RAND Corporation study.A greater density of housing also may encourage walking, but only once density reaches a relatively high level, according to the RAND Health study that is one of the first to test whether urban design recommendations for creating walkable communities may help achieve their goal. [click link for full article]...more >> |
| Early Puberty In Girls Due to Being Overweight As A Toddler | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-05 | | US scientists have shown that being overweight as a toddler increases the chance that a girl will reach puberty early.The study from the University of Michigan's Mott Children's Hospital is published in the journal Pediatrics.Dr Joyce Lee, the lead author, and colleagues used the data on 354 girls from age 3 who were enrolled in the National Institute of Child Health and Human Development (NICHD) Study of Early Child Care and Youth Development (SECCYD). [click link for full article]...more >> |
| Staying Busy And Active Contributes To Longer Life | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-05 | | Physical activity as the elixir of youth might seem like old news, but there's a new twist, according to the March issue of Mayo Clinic Women's HealthSource. For the best chance of a long, healthy life, marathon training is not required. But, staying busy and active might be.Research published last year found that any activity that contributed to energy expenditure in older adults may help prolong life. [click link for full article]...more >> |
| Slimming World Voted Best Diet Aid | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-05 | | Slimming World proved such a success with online visitors to Review Centre during the last year that it easily won the best diet aid award for 2006, beating competition from 34 other well known diets and diet aids.The award is based on averages of ratings and user comments submitted by customers to Review Centre in 2006, and also for overall ratings and comments featured at the Review Centre site. [click link for full article]...more >> |
| Exercise, Diet, Supplements Play Role In Lowering Cholesterol Without Drugs | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-05 | | When it's time to rein in cholesterol, the go-to prescription is usually statins. These medications can reduce low-density lipoprotein (LDL) cholesterol -- the bad cholesterol -- from 25 percent to 50 percent. But for a variety of reasons, statins aren't an option for everyone.The March issue of Mayo Clinic Women's HealthSource outlines other ways to lower cholesterol levels. [click link for full article]...more >> |
| Asia-Pacific Has The Biggest Diabetes Burden In The World | | Diabetes News From Medical News Today -- 2007-03-05 | | Given that in the year 2000 an estimated 83 million people in the Asia-Pacific region were living with type 2 diabetes, representing almost half of the 171 million people with diabetes worldwide, these findings highlight the huge impact that diabetes prevention and awareness campaigns could have in the area. In Australia alone, diabetes is responsible for 4,000 fatal heart attacks and strokes each year. [click link for full article]...more >> |
| SIR: 'Rapid Lysis' Dissolves Severe DVT | | MedPage Today Endocrinology -- 2007-03-05 | | SEATTLE -- Combining thrombolytic medication with a clot removal device effectively dissolves extensive deep vein thrombosis (DVT) in a single session, according to a retrospective study....more >> |
| CDEP: Lipid Spike Seen When Hormone Therapy Stops | | MedPage Today Endocrinology -- 2007-03-05 | | ORLANDO, Fla. -- When post menopausal women stop hormone replacement therapy, LDL cholesterol levels are likely to spike, leading many physicians to prescribe statins that may be superfluous, according to researchers here....more >> |
| Abdominal Obesity Is the Bane of Latin America | | Medscape Diabetes Headlines -- 2007-03-05 | Abdominal obesity seems to be the most important risk factor when it comes to MI in Latin America, a new analysis of the INTERHEART study has found.
Heartwire
Lisa Nainggolan...more >> |
| Pathohistological classification of pituitary tumors: 10 years of experience with the German Pituitary Tumor Registry | | Endocrinology News -- 2007-03-05 | European Journal of Endocrinology
Wolfgang Saeger, et al. – In 1996, the German Registry of Pituitary Tumors was founded by the Pituitary Section of the German Society of Endocrinology as a reference center for collection and consultant pathohistological studies of pituitary tumors. The experiences of the first 10 years of this registry based on 4122 cases will herein be reported. The data supplement former collections of the years 1970–1995 with 3480 surgically removed tumors or lesions of the pituitary region...more >> |
| Prevalent Rheumatoid Arthritis and Diabetes Among NHANES III Participants Aged 60 and Older | | Endocrinology News -- 2007-03-05 | Journal of Rheumatology
Julia F. Simard, et al. - Conclusion: While this study cannot definitively rule out a modest non-null association, we can conclude that there is no evidence of a strong cross-sectional association between prevalent RA and diabetes in subjects aged >= 60 years. Future longitudinal studies with more participants with RA are required to further evaluate a possible association between RA and the incidence of diabetes...more >> |
| Glycemic and Risk Factor Control in Type 1 Diabetes | | Endocrinology News -- 2007-03-05 | Diabetes Care
Eeg-Olofsson, K., et al. – Are recently updated treatment goals making a difference?<br>><b>Summary: </b> This study investigated the clinical characteristics of a large type 1 diabetic population and to evaluate the degree of fulfillment of recently updated treatment goals. A1C levels, treatment, and risk factors were analyzed in two cross-sectional samples of 9,424 patients in 1997 and 13,612 patients in 2004 and in a smaller longitudinal sample from 1997 to 2004. <br><b>Outcomes: </b>In this large cohort of type 1 diabetic patients, there was a slow improvement in glycemic and risk factor control from 1997 to 2004, although the gap between the clinical results and current Swedish and American treatment goals is still unsatisfactory. It is crucial that additional measures be taken to improve risk factor control in type 1 diabetic patients...more >> |
| Serum Zinc Level and Coronary Heart Disease Events in Patients With Type 2 Diabetes | | Endocrinology News -- 2007-03-05 | Diabetes Care
Soinio, M., et al. – Low serum zinc level a risk factor for CHD events in this diabetic population.<br>><b>Summary: </b> Serum zinc values were obtained from a group of 1,059 patients with type 2 diabetes, aged 45 - 64 years. Mean duration of diabetes was 8 years. CHD mortality and the incidence of nonfatal MI were assessed in a 7-year follow-up.<br><b>Outcomes: </b> Patients with a serum zinc concentration of lower 14.1 µmol/l at baseline had a higher risk for death from CHD than patients with serum zinc level above 14.1 µmol/l. The risks for fatal or nonfatal MI were 30.5 and 22.0%, respectively. A Cox regression analyses determined that low serum zinc concentration was significantly associated with CHD mortality and all CHD events even after adjustment for confounding variables...more >> |
| Prediction of Diabetic Nephropathy Using Urine Proteomic Profiling 10 Years Prior to Development of Nephropathy | | Endocrinology News -- 2007-03-05 | Diabetes Care
Hasan H. Otu, PHD., et al. – Is proteomic profiling valuable in identifying progression of diabetic nephropathy?<br>><b>Summary: </b> In a nested case-control study of Pima Indians with type 2 diabetes, baseline and 10-year urine samples were examined. Thirty one case subjects developed diabetic nephropathy over 10 years. The same number of control subjects were matched to case subjects according to diabetes duration, age, sex, and BMI but remained normoalbuminuric over the same 10 years. The study examined whether proteomic technologies could identify novel urine proteins associated with subsequent development of diabetic nephropathy.<br><b>Outcomes: </b>Urine proteomic profiling identifies normoalbuminuric subjects with type 2 diabetes who subsequently develop diabetic nephropathy. Further studies are needed to characterize the specific proteins involved in this early prediction...more >> |
| Superiority of Small Islets in Human Islet Transplantation | | Endocrinology News -- 2007-03-05 | Diabetes
Lehmann, R., et al. – Small islet size is a key factor in transplantation success.<br>><b>Summary: </b> This research assessed insulin secretion of large and small islets and quantified cell death during hypoxic conditions simulating the intraportal transplant environment. In the clinical setting, the influence of transplanted islet size on insulin production in patients with type 1 diabetes was analysed.<br><b>Outcomes: </b> Results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture. Islet size seems to be a key factor determining human islet transplantation outcome...more >> |
| Effect of Acute Exercise on AMPK Signaling in Skeletal Muscle of Subjects With Type 2 Diabetes | | Endocrinology News -- 2007-03-05 | Diabetes
Apiradee Sriwijitkamol, et al. – Activation of AMP-activated protein kinase (AMPK) by exercise induces several cellular processes in muscle. Exercise activation of AMPK is unaffected in lean (BMI 25 kg/m2) subjects with type 2 diabetes. However, most type 2 diabetic subjects are obese (BMI >30 kg/m2), and exercise stimulation of AMPK is blunted in obese rodents. We examined whether obese type 2 diabetic subjects have impaired exercise stimulation of AMPK, at different signaling levels, spanning from the upstream kinase, LKB1, to the putative AMPK targets...more >> |
| Prospective randomized controlled study of Hydrofiber® dressing containing ionic silver or calcium alginate dressings in non-ischaemic diabetic foot ulcer | | Endocrinology News -- 2007-03-05 | Diabetic Medicine
Jude, E. B, et al. – Are there measurable clinical effects of a primary wound dressing containing silver? <br>><b>Summary: </b> A prospective, multicentre study compared clinical efficacy and safety of AQUACEL® Hydrofiber® dressings containing ionic silver (AQAg) with those of Algosteril® calcium alginate (CA) dressings in managing out-patients with Type 1 or 2 diabetes mellitus and non-ischaemic Wagner Grade 1 or 2 DFUs. <br><b>Outcomes: </b> When added to standard care with appropriate off-loading, AQAg silver dressings were associated with favourable clinical outcomes compared with CA dressings, specifically in ulcer depth reduction and in infected ulcers requiring antibiotic treatment. This study reports the first significant clinical effects of a primary wound dressing containing silver on DFU healing...more >> |
| Thiazolidinediones and vascular damage | | Endocrinology News -- 2007-03-05 | Current Opinion in Endocrinology and Diabetes
Goldberg, Ronald B, - Will use of these drugs prevent cardiovascular disease?<br>><b>Summary: </b>The purpose of this review was to investigate the possibility of thiazolidinedione agents having vasculoprotective effects and if so whether these are associated with the prevention of cardiovascular disease.<br><b>Outcomes: </b>The weight of the experimental, subclinical and clinical assessments of the effects of these agents supports the contention that they are vasculoprotective. In the final analysis their use in clinical practice to prevent cardiovascular disease will mostly depend on whether clinical trials consistently demonstrate that they reduced cardiovascular events...more >> |
| Dipeptidyl peptidase-4 inhibitors and the management of type 2 diabetes mellitus | | Endocrinology News -- 2007-03-05 | Current Opinion in Endocrinology and Diabetes
Rosenstock, Julio, et al. – Long term studies needed to confirm potential of glycemic control.<br>><b>Summary: </b> The purpose of this research was to review recent clinical trials of oral dipeptidyl peptidase-4 inhibitors and examine their role in managing type 2 diabetes mellitus. <br><b>Outcomes: </b>Oral dipeptidyl peptidase-4 inhibitors may prove valuable in the treatment of diabetes, given their effectiveness in reducing glycated hemoglobin with neutral weight effects and without the adverse events associated with other agents. Dipeptidyl peptidase-4 inhibitors appear to improve islet function and may modify the course of diabetes; this, however, must be confirmed with long-term controlled studies to demonstrate sustained glycemic control that translates into [beta]-cell preservation...more >> |
| Increased extracellular signal regulated kinases phosphorylation in the adrenal gland in response to chronic ACTH treatment | | Endocrinology News -- 2007-03-05 | Journal of Endocrinology
Jorge G Ferreira, et al. - ACTH released from the pituitary acts through activation of cAMP/PKA in adrenocortical cells stimulating steroidogenesis. Although ACTH was originally thought to have anti-proliferative effects on the adrenal, recently it has been described that it could also have proliferative effects acting through other signalling cascades. This is also relevant in humans given the increased levels of ACTH occurring together with adrenal cortex hyperplasia observed in Cushing’s disease and possibly in other situations such as chronic stress...more >> |
| Insulin Secretion and Insulin Sensitivity in Relation to Fasting Glucose in Healthy Subjects | | Endocrinology News -- 2007-03-05 | Diabetes Care
Bo Ahrén, MD, PHD., - Does high, but still normal, fasting glucose contribute to augmented insulin secretion?<br>><b>Summary: </b> A total of 148 healthy 50+ year old women underwent a glucose-dependent arginine stimulation test and a 2-h euglycemic-hyperinsulinemic clamp. In the arginine test, arginine (5 g) was injected intravenously under baseline (fasting) conditions and after raising the glucose levels to 15 and >28 mmol/l. From this test, the acute insulin response (AIR) to arginine during the three glucose levels (AIR1, AIR2, and AIR3) were estimated.<br><b>Outcomes: </b> The researchers concluded that 1) raised fasting glucose augments baseline and maximal arginine-induced insulin secretion in healthy subjects, and 2) this is associated with reduced insulin sensitivity. This suggests that high, but still normal, fasting glucose may contribute to the augmented insulin secretion in subjects with low insulin sensitivity...more >> |
| Prospective Study of Hyperglycemia and Cancer Risk | | Endocrinology News -- 2007-03-05 | Diabetes Care
Pär Stattin, MD, PHD., et al. – Is there an association between abnormal glucose metabolism and the development of cancer?<br>><b>Summary: </b> In the Västerbotten Intervention Project of northern Sweden, fasting and postload plasma glucose concentrations were available for 33,293 women and 31,304 men and 2,478 incident cases of cancer were identified. Relative risk (RR) of cancer for levels of fasting and postload glucose was calculated with the use of Poisson models, with adjustment for age, year of recruitment, fasting time, and smoking status. Repeated measurements 10 years after baseline in almost 10,000 subjects were used.<br><b>Outcomes: </b> Risk of cancer of the pancreas, endometrium, urinary tract, and of malignant melanoma was statistically significantly associated with high fasting glucose. The association of hyperglycemia with total cancer risk in women and in women and men combined for several cancer sites, independently of obesity, provides further evidence for an association between abnormal glucose metabolism and cancer...more >> |
| Effects of anethum graveolens and garlic on lipid profile in hyperlipidemic patients | | Atherosclerosis/Lipids News -- 2007-03-05 | Lipids in Health and Disease
Javad Kojuri, et al. – Hyperlipidemia as a major risk factor of atherosclerosis is treated with different drugs...Conclusion: Anethum has no significant effect on lipid profile, but garlic tablet has significant favorable effect on cholesterol, LDL-cholesterol, and HDL-cholesterol. Garlic may play an important role in therapy of hypercholesterolemia...more >> |
| Approximation of total visceral adipose tissue with a single magnetic resonance image | | Atherosclerosis/Lipids News -- 2007-03-05 | American Journal of Clinical Nutrition
Ellen W Demerath, et al. – A single axial image measured between the 4th and 5th lumbar vertebrae (L4-L5) is most frequently chosen to approximate total abdominal visceral adipose tissue (VAT) volume, but growing evidence suggests that this measurement site is not ideal...Conclusion: A single MR image located approximately at the L3 vertebra can accurately estimate total VAT volume in blacks and whites of both sexes...more >> |
| Dietary -linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects | | Atherosclerosis/Lipids News -- 2007-03-05 | American Journal of Clinical Nutrition
Guixiang Zhao, et al. – Atherosclerosis is a chronic inflammatory disease. We previously reported that a diet high in alpha linolenic acid (ALA) reduces lipid and inflammatory cardiovascular disease risk factors in hypercholesterolemic subjects...Conclusion: Increased intakes of dietary ALA elicit antiinflammatory effects by inhibiting IL-6, IL-1beta, and TNF-alpha production in cultured PBMCs. Changes in PBMC ALA and eicosapentaenoic acid (derived from dietary ALA) are associated with beneficial changes in TNF-alpha release...more >> |
| Increased Expression of Visfatin in Macrophages of Human Unstable Carotid and Coronary Atherosclerosis | | Atherosclerosis/Lipids News -- 2007-03-05 | Circulation
Tuva B. Dahl, MSc., et al. – Although the participation of inflammation in atherogenesis is widely recognized, the identification of the different components has not been clarified. In particular, the role of inflammation in plaque destabilization is not fully understood...Conclusion: Our findings suggest that visfatin should be regarded as an inflammatory mediator, localized to foam cell macrophages within unstable atherosclerotic lesions, that potentially plays a role in plaque destabilization...more >> |
| Safety of Lovastatin/Extended Release Niacin Compared With Lovastatin Alone, Atorvastatin Alone, Pravastatin Alone, and Simvastatin Alone | | Atherosclerosis/Lipids News -- 2007-03-05 | American Journal of Cardiology
Alsheikh-Ali, Alawi A. MD., et al. – Are the label warnings about increased risk of adverse events with statin and niacin combinations valid?<br>><b>Summary: </b>A comparison review of the rate of adverse event reports (AERs) received by the United States Food and Drug Administration from 1999 to March 2005 associated with the combination of lovastatin/niacin-extended release (ER) with those of lovastatin or niacin-ER alone, and other commonly used statins.The prevalence of concomitant niacin-ER therapy in the statin-associated AERs was also calculated.<br><b>Outcomes: </b>The amount of serious AERs associated with the combination lovastatin/niacin-ER was similar to that of lovastatin or niacin-ER alone, and significantly less than that of atorvastatin or simvastatin used alone. The rates of liver and rhabdomyolysis AERs associated with lovastatin/niacin-ER were similar to those of the other statins or niacin-ER uses alone and lower than those associated with simvastatin alone. The incidence of niacin-ER use in statin-associated AERs was less than 1%. The findings indicate that statins can safely be used in combination as indicated in the national guidelines...more >> |
| Angiogenic Role of LYVE-1–Positive Macrophages in Adipose Tissue | | Atherosclerosis/Lipids News -- 2007-03-05 | Circulation Research
Chung-Hyun Cho, et al. – Here we report the discovery of a characteristic dense vascular network (DVN) in the tip portion of epididymal adipose tissue in adult mice. The DVN is formed by angiogenesis rather than by vasculogenesis, and has functional blood circulation. This DVN and its subsequent branching may provide a new functional route for adipogenesis...more >> |
| Complications Following Hip Replacement More Common In Obese Patients, Especially Women | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-04 | | Obese patients tend to have a higher prevalence of total hip replacements due to a higher incidence of hip osteoarthritis. This is of particular concern in light of the trend in rising rates of obesity in developed countries. A new study published in the March 2007 issue of [click link for full article]...more >> |
| Walkability Study Sheds Light Around Light Rail Stops In Portland & San Francisco Bay Area | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-04 | | Got a train to catch? The walk to the nearest stop has been put under scientific scrutiny, looking at distances involved and the environment along the way.The findings, which include the discovery that people often walk farther than they had thought despite their desire to minimize time and distance, are detailed in an award-winning paper by researchers at the University of Oregon and San Jose State University. A goal of the research - conducted in Portland, Ore. [click link for full article]...more >> |
| Excessive TV Viewing By Children Is Linked To Poor Eating Habits | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-04 | | The more a 3-year-old watches television, the more he or she consumes sugary drinks, and extra calories, Harvard researchers said at the American Heart Association's 47th Annual Conference on Cardiovascular Disease Epidemiology and Prevention."For every one-hour increase in TV viewing per day, we found higher intakes of sugar-sweetened beverages including juice (one extra serving per week) and total calories (46.3 more kcal/day)," said Sonia Miller, B.A. [click link for full article]...more >> |
| Schools Help Hold The Line Against Childhood Obesity, Study Says | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-04 | | Schools do more to help prevent obesity among children than they do to cause it, new research suggests.A nationwide study found that one measure of obesity rose more than twice as fast when kindergarten and first-grade students were on summer vacation than when they were in school.And obese children were helped most by being in school: they gained weight no faster than other children did during the school year. [click link for full article]...more >> |
| Simple Solutions To Postpartum Weight Retention | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-04 | | Women aiming to shed after pregnancy pounds should add daily walks and limit TV time and trans fats, according to a new study by Harvard researchers. "The childbearing years are a time of particular risk for weight gain in women," said lead author Emily Oken, M.D. "Modifiable behaviors in that early postpartum period such as diet, television viewing and walking can influence a woman's risk of retaining weight. [click link for full article]...more >> |
| New Science-Based Guide To Natural Fat-Loss | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-02 | | American consumers have long been skeptical about weight-loss supplements, and rightly so. With dozens of nutrients, herbs, and food extracts being marketed as aids for weight loss, there is shockingly little reliable information available concerning the safety and efficacy of any given product. [click link for full article]...more >> |
| Diabetes Will Be A Bigger Burden Than Predicted, The Lancet | | Diabetes News From Medical News Today -- 2007-03-02 | | WHO has predicted a 39% rise in the worldwideprevalence of diabetes between 2000 and 2030, butan Article in this week's Lancet indicates that this figuremight be a gross underestimation. Using populationbaseddata from Ontario, Lorraine Lipscombe andcolleagues have observed a 69% increase in theprevalence of known diabetes from 1995 to 2005; anincrease that already exceeds WHO's predicted rate. [click link for full article]...more >> |
| Study Confirms That Significant Insulin Dose Errors Can Result When Blood Glucose Meters Are Miscoded | | Diabetes News From Medical News Today -- 2007-03-02 | | When persons with diabetes use miscoded blood glucose meters to determine how much insulin to take, significant errors in insulin dose can result that may potentially lead to short- and long-term health complications, according to findings of a new study just published in the Journal of Diabetes Science and Technology (http://www.journalofdst.org). [click link for full article]...more >> |
| 'Mild' IVF Reduces Multiple Pregnancies | | MedPage Today Endocrinology -- 2007-03-02 | | UTRECHT, The Netherlands -- IVF rates for term live births after "mild" ovarian stimulation with single-embryo transfer equaled the rates for standard stimulation with two-embryo transfer, Dutch researchers reported....more >> |
| Chronic Kidney Disease Prevalence Creeps Up | | MedPage Today Endocrinology -- 2007-03-02 | | ATLANTA -- An estimated 16.8% of the U.S. population ages 20 and older has chronic kidney disease, reported researchers from the National Center for Chronic Disease Prevention and Health Promotion....more >> |
| Reaffirming the Public Good | | Medscape Diabetes Headlines -- 2007-03-02 | Darrell G. Kirch, MD, the new President of the AAMC in Washington, DC, urges us to collaboratively restore three of our most vital public goods: higher education, scientific research, and healthcare.
Medscape General Medicine...more >> |
| The association between TSH within the reference range and serum lipid concentrations in a population-based study | | Endocrinology News -- 2007-03-02 | European Journal of Endocrinology
Asvold, B., et al. – Is there a significant link between TSH levels and lipid concentrations?<br>><b>Summary: </b> A cross-sectional, population-based study was carried out using 30,656 subjects without known thyroid disease. Using general linear models, mean concentrations of total serum cholesterol, low-density lipoprotein (LDL) cholesterol, non-high-density lipoprotein (HDL) cholesterol, HDL cholesterol and triglycerides across categories of TSH were calculated for each individual. <br><b>Outcomes: </b>Within the range of TSH that is considered clinically normal, it was found that increasing levels of TSH were associated with less favourable lipid concentrations. The association with serum lipids was linear across the entire reference range of TSH...more >> |
| Adipose Tissue as a Modulator of Clinical Inflammation: Does Obesity Reduce the Prevalence of Rheumatoid Arthritis? | | Endocrinology News -- 2007-03-02 | Journal of Rheumatology
Tamas Bartfai, et al. - Conclusion: Although both RA and obesity have been reported to be characterized by high serum levels of inflammatory cytokines, the frequency of one disorder was not increased in the other. We propose that the lack of association in prevalence between the 2 inflammatory states, rather than reflecting a post-hoc effect of the disease on BMI, is a function of the relative amounts of pro- and antiinflammatory mediators produced in adipose tissue, which under many circumstances leads to an overall systemic antiinflammatory tone...more >> |
| US adults average spending on diabetes treatment increases over 7 years | | Endocrinology News -- 2007-03-02 | Formulary
Between 1996 and 2003, average constant dollar expenditures on prescription medications by adults with >=1 medical event for the treatment of diabetes increased 87.3% in those aged 18 to 44 years, 114.9% in those aged 45 to 64 years, and 61.4% in those aged >=65 years...more >> |
| Growth hormone stimulates osteoprotegerin expression and secretion in human osteoblast-like cells | | Endocrinology News -- 2007-03-02 | Journal of Endocrinology
E Mrak, et al. – It is presently thought that osteoprotegerin (OPG) is a cytokine involved in the regulation of osteoblast/osteoclast crosstalk and maintenance of bone mass. Recent studies showed that GH replacement therapy in GH-deficient patients was able to induce a significant increase of OPG in the plasma, as well as in the cortical and the trabecular bone...more >> |
| Chronic testosterone treatment induces selective insulin resistance in subcutaneous adipocytes of women | | Endocrinology News -- 2007-03-02 | Journal of Endocrinology
Corbould, A., - Do androgens influence insulin-mediated glucose metabolism in adipose cells?<br>><b>Summary: </b>Preadipocytes harvested from s.c. adipose tissue of healthy women were differentiated in vitro, then treated with testosterone (T) and/or androgen receptor (AR) antagonists (cyproterone acetate, flutamide) for 48 hours. Maximal insulin-stimulated glucose uptake (insulin 10 nM) and increment following insulin stimulation were significantly impaired in cells treated with T 10 and 100 nmol/l.<br><b>Outcomes: </b> The findings of this study are relevant to understanding the pathogenesis of insulin resistance in hyperandrogenic women...more >> |
| Cholesteryl ester transfer protein and hyperalphalipoproteinemia in Caucasians | | Atherosclerosis/Lipids News -- 2007-03-02 | Journal of Lipid Research
Wim A. van der Steeg, et al. – It is unclear whether cholesteryl ester transfer protein (CETP) contributes to high density lipoprotein cholesterol (HDL-C) levels in hyperalphalipoproteinemia (HALP) in Caucasians. Moreover, even less is known about the effects of hereditary CETP deficiency in non-Japanese. We studied 95 unrelated Caucasian individuals with HALP. No correlations between CETP concentration or activity and HDL-C were identified...more >> |
| Consistently Stable or Decreased Body Mass Index in Young Adulthood and Longitudinal Changes in Metabolic Syndrome Components: The Coronary Artery Risk Development in Young Adults Study | | Atherosclerosis/Lipids News -- 2007-03-02 | Circulation
Lloyd-Jones, Donald M. MD, ScM., et al. – Is BMI the key to halting the the progression of metabolic syndrome risk factors with advancing age?
<br>><b>Summary: </b>Prospective study of 1358 men and 1321 women ages 18 to 30 years enrolled in from 1985 to 1986, were stratified into groups by baseline BMI and change in BMI
Patients were monitored for changes in metabolic syndrome components over 15 years.
<br><b>Outcomes: </b>Over 15 years, participants whose BMI remained stable BMI had essentially unchanged levels of metabolic syndrome components, regardless of their baseline BMI, whereas those with an increased BMI had progressively worsening levels. The incidence of metabolic syndrome at year 15 was was lower at 2.2% in the stable BMI group versus 18.8% in the group whose BMI increased. The incidence of developing metabolic syndrome with advancing age can be decreased by maintaining a stable BMI over time...more >> |
| Relation of Osteoprotegerin to Coronary Calcium and Aortic Plaque | | Atherosclerosis/Lipids News -- 2007-03-02 | American Journal of Cardiology
Moeen Abedin MD., et al. – Circulating osteoprotegerin (OPG) has been shown to be elevated in patients with vascular disease. The role of OPG as a biomarker for atherosclerosis in a large, unselected population is not well known...Conclusion: Plasma OPG is independently associated with CAC and aortic plaque in an unselected population, suggesting it may be a novel biomarker for atherosclerosis in humans...more >> |
| Discontinuation of Lipid Modifying Drugs Among Commercially Insured United States Patients in Recent Clinical Practice | | Atherosclerosis/Lipids News -- 2007-03-02 | American Journal of Cardiology
Kamal-Bahl, Sachin J. PhD., et al. – Are lipid modifying drugs (LMD) being discontinued too soon in clinical practice?
<br>><b>Summary: </b>Observational study using claims from the Ingenix Lab/Rx Database were used to identify patients aged ?20 years who were being treated with statins, extended-release niacin, fibrates, bile acid sequestrants, or ezetimibe from January 1, 2001, to June 30, 2003.
The claims were reviewed to determine at which point treatment with the LMDs was discontinued
<br><b>Outcomes: </b>Tne incidence of discontinuation after 1 year was 68.3% in patients treated with bile acid sequestrants, 55.4% with extended-release niacin users, 39.9% with fibrates, 33.0% with ezetimibe, and 28.9% with statins. There were high rates of discontiuations despite current knowledge about the benefits of long-term therapy...more >> |
| Calculation of arterial wall temperature in atherosclerotic arteries: Effect of pulsatile flow, arterial geometry, and plaque structure | | Atherosclerosis/Lipids News -- 2007-03-02 | BMC Medical Imaging
Obdulia Ley, et al. - Conclusions: The results indicate that direct temperature measurements should be taken (1) as close as possible to the plaque/lumen surface, as the calculations show a significant drop in temperature within 120 micrometers from the plaque surface; (2) in the presence of blood flow, temperature measurement should be performed in the downstream edge of the plaque, as it shows higher temperature independently of the arterial geometry; and (3) it is necessary to perform measurements at a sampling rate that is higher than the cardiac cycle...more >> |
| Mitochondrial Dysfunction in Atherosclerosis | | Atherosclerosis/Lipids News -- 2007-03-02 | Circulation Research
Nageswara R. Madamanchi, et al. – Increased production of reactive oxygen species in mitochondria, accumulation of mitochondrial DNA damage, and progressive respiratory chain dysfunction are associated with atherosclerosis or cardiomyopathy in human investigations and animal models of oxidative stress...more >> |
| Characterization of the Natural Killer T-Cell Response in an Adoptive Transfer Model of Atherosclerosis | | Atherosclerosis/Lipids News -- 2007-03-02 | American Journal of Pathology
Paul A. VanderLaan, et al. - Natural killer T (NKT) cells have recently been implicated in atherogenesis, primarily for their ability to recognize and respond to lipid antigens. Because the atherosclerotic lesion is characterized by the retention and modification of lipids in the vascular wall, NKT cells may be involved in promoting the local vascular inflammatory response...more >> |
| The molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin | | Atherosclerosis/Lipids News -- 2007-03-02 | Journal of Lipid Research
Dawn E. Telford, et al. – The combination of ezetimibe, an inhibitor of Niemann-Pick C1-like 1 protein (NPC1L1), and an HMG-CoA reductase inhibitor decreases cholesterol absorption and synthesis. In clinical trials, ezetimibe plus simvastatin produces greater LDL-cholesterol reductions than does monotherapy. The molecular mechanism for this enhanced efficacy has not been defined...more >> |
| Usefulness Of Cardiovascular Disease Test Questioned | | Cholesterol News From Medical News Today -- 2007-03-02 | | Researchers with Dartmouth Medical School and the Veterans Affairs Outcomes Group at the White River Junction (Vt.) VA Medical Center are questioning the usefulness of the C-Reactive Protein (CRP) test for guiding decisions about the use of cholesterol-lowering medication. [click link for full article]...more >> |
| Cholesterol In Stroke Patients Exceeds National Guidelines | | Cholesterol News From Medical News Today -- 2007-03-02 | | Many stroke patients have cholesterol higher than national guidelines recommend that, if managed, may have prevented the stroke from happening, according to a study published in the February 27, 2007, issue of Neurology®, the scientific journal of the American Academy of Neurology. The study of 1,040 people hospitalized for stroke or transient ischemic attack (TIA) found that 27 percent had cholesterol higher than recommended by national guidelines. [click link for full article]...more >> |
| Children Gain Weight Faster During Summer Vacation | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-03-01 | | Even though many schools fall short when it comes to offering daily physical education and balanced meals, children are more likely to pack on pounds during summer break than during the school year. A study based on twice-yearly body mass index (BMI) measurements from 5,380 children in 310 schools found that BMI gains were faster and more variable during summer vacation than during the kindergarten and first grade school years. [click link for full article]...more >> |
| New Blood Glucose Meters, Contour® And Breeze®2, Now Available In Pharmacies Nationwide, USA | | Diabetes News From Medical News Today -- 2007-03-01 | | Bayer Diabetes Care, a division of Bayer HealthCare LLC and a member of the Bayer Group (NYSE: BAY), announced today the availability of the latest advances in their line of blood glucose meters: the new CONTOUR® and BREEZE®2 meters. As an innovator of meters with No Coding™ technology, Bayer's new meters now offer shorter testing times and easier functionality. [click link for full article]...more >> |
| Fatty Liver and the Metabolic Syndrome | | Medscape Diabetes Headlines -- 2007-03-01 | Nonalcoholic fatty liver disease and its subset nonalcoholic steatohepatitis represent the liver manifestations of insulin resistance.
Current opinion in gastroenterology...more >> |
| Fatty acid metabolism in adipocytes: Functional analysis of fatty acid transport proteins 1 and 4 | | Atherosclerosis/Lipids News -- 2007-03-01 | Journal of Lipid Research
Sandra Lobo, et al. – The role of fatty acid transport protein 1 (FATP1) and FATP4 in facilitating adipocyte fatty acid metabolism was investigated using stable FATP1 or FATP4 knockdown (kd) 3T3-L1 cell lines derived from retrovirus-delivered short hairpin RNA (shRNA). Decreased expression of FATP1 or FATP4 did not affect preadipocyte differentiation or the expression of FATP1...more >> |
| Seven Keys To Reduce Cholesterol - Free Special Report From Johns Hopkins Health Alerts | | Cholesterol News From Medical News Today -- 2007-03-01 | | Johns Hopkins Health Alerts today released an important new Special Report, Seven Keys To Reduce Cholesterol, in order to reduce the risk of heart attack and improve one's overall health. The government's National Cholesterol Education Program (NCEP) estimates that at least 65 million Americans have high cholesterol levels that merit treatment with dietary and other lifestyle changes designed to lower cholesterol. [click link for full article]...more >> |
| Garlic Does Not Appear To Lower Cholesterol Levels | | Cholesterol News From Medical News Today -- 2007-03-01 | | Three forms of garlic including raw garlic and two types of commercial garlic supplements did not significantly reduce low-density lipoprotein (LDL or "bad") cholesterol during a six-month trial, according to results published in the February 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. [click link for full article]...more >> |
| Magic Beans -- Anti-obesity Soya Could Help Prevent Diabetes | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-28 | | A diet rich in black soya beans could help control weight, lower fat and cholesterol levels, and aid in the prevention of diabetes, reports Lisa Richards in Chemistry & Industry, the magazine of the SCI.Yellow soya has already been hailed for its cholesterol lowering capabilities; this is one of the reasons why frozen food manufacturer Birds Eye has added the beans to its range. [click link for full article]...more >> |
| Patients With Type 1 Diabetes Don't Wake In Response To Hypoglycemia | | Diabetes News From Medical News Today -- 2007-02-28 | | A study of 16 patients with type 1 diabetes mellitus (T1DM) and 16 normal individuals shows that only one of the 16 T1DM patients, as compared to ten healthy control participants, awakened upon hypoglycemia.Bernd Schultes and colleagues from the University of Lubeck induced hypoglycemia with insulin under controlled conditions and then assessed sleep with polysomography. A fall in plasma glucose to 2. [click link for full article]...more >> |
| Growth Hormone To Boost Athletic Performance Risks Diabetes | | Diabetes News From Medical News Today -- 2007-02-28 | | Use of growth hormone to boost athletic performance can lead to diabetes, reports a study published ahead of print in the British Journal of Sports Medicine.The study reports the case of a 36 year old professional body-builder who required emergency care for chest pain.He had lost 40 kg in 12 months, during which he had also experienced excessive urination, thirst, and appetite. [click link for full article]...more >> |
| Glucose Intolerance Linked To Cancer Risk In Women | | Diabetes News From Medical News Today -- 2007-02-28 | | High blood glucose levels -- even before they reach the level needed for a diagnosis of diabetes -- may signal an increased risk for cancer in women, according to a new study being published in the March issue of Diabetes Care. The March journal also includes a study that found a link between high levels of persistent organic pollutants (POPs) in a person's bloodstream and insulin resistance, a precursor for type 2 diabetes. [click link for full article]...more >> |
| Journal Scan - Type 2 Diabetes | | Medscape Diabetes Headlines -- 2007-02-28 | The third issue of this special report focuses on A Diabetes Outcome Progression Trial and other studies presented at the International Diabetes Federation World Congress.
(CME)
Medscape Diabetes & Endocrinology
Gregory Nichols...more >> |
| Expert Column - A Diabetes Outcome Progression Trial (ADOPT) | | Medscape Diabetes Headlines -- 2007-02-28 | The third issue of this special report focuses on A Diabetes Outcome Progression Trial and other studies presented at the International Diabetes Federation World Congress.
(CME)
Medscape Diabetes & Endocrinology
Steven Haffner...more >> |
| Call for Papers | | Medscape Diabetes Headlines -- 2007-02-28 | Submit your paper to Medscape's MEDLINE-PUBMED-indexed medical journal, Medscape General Medicine.
Medscape Family Medicine...more >> |
| Healthcare Systems and Motivation | | Medscape Diabetes Headlines -- 2007-02-28 | The author discusses the historic roots of the US healthcare "system" and the self- and other-directed motivations of physicians.
Medscape General Medicine...more >> |
| Type 2 Diabetes: The Latest Research, Volume 3 | | Medscape Diabetes Headlines -- 2007-02-28 | | The third issue of this special report focuses on A Diabetes Outcome Progression Trial and other studies presented at the International Diabetes Federation World Congress. (CME)...more >> |
| Scheduling Of Orlistat - National Drugs And Poisons Schedule Committee, Australia | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-27 | | The National Drugs and Poisons Schedule Committee (NDPSC) reconsidered the scheduling and advertising status of orlistat (contained in the medicine Xenical) at its February 2007 meeting. After reviewing a large number of submissions from consumer, industry and professional bodies, the NDPSC has decided that orlistat should be retained in Schedule 3 as a Pharmacist Only medicine. [click link for full article]...more >> |
| Chain Restaurants Encourage Americans To Over Eat Says Watchdog | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-27 | | A US watchdog has charged chain restaurants with encouraging Americans to over eat. It is not unusual to find a single meal packing in more than several days' worth of calories says the US Center for Science in the Public Interest (CSPI).CSPI are calling for all chain restaurants to show nutritional information, including the calorie value of each dish, in their menus. [click link for full article]...more >> |
| Long-Term Safety Data Show The LAP-BAND(R) Adjustable Gastric Banding System Results In Fewer Complications Compared To Gastric Bypass | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-27 | | Researchers from Legacy Good Samaritan Obesity Institute announced today the results from a 5-year study of the safety of laparoscopic adjustable gastric banding (LAGB) compared to laparoscopic Roux-en Y gastric bypass (LRYGB), two bariatric surgical procedures performed in the United States for the treatment of morbid obesity. All patients undergoing LAGB received the LAP-BAND(R) System, which is the only FDA-approved adjustable implant device for individualized weight loss. [click link for full article]...more >> |
| Obese British boy to stay with family
(Reuters)
| | Yahoo! News: Weight Loss News -- 2007-02-27 | | Reuters - British social workers decided on
Tuesday to allow an eight-year-old boy who weighs almost 200
pounds (91 kg) to remain at home with his mother, who has
refused to stop feeding him junk food....more >> |
| PKC-Epsilon Links Fat To Insulin Resistance | | Diabetes News From Medical News Today -- 2007-02-27 | | The accumulation of fat in the liver (hepatic steatosis) can result in non-alcoholic fatty liver disease, which is associated with hepatic insulin resistance and type 2 diabetes mellitus. However, the mechanisms by which fat accumulation leads to hepatic insulin resistance have not been well characterized. [click link for full article]...more >> |
| One Step Closer To A Potential Cure For Diabetes | | Diabetes News From Medical News Today -- 2007-02-27 | | For the millions of people worldwide who are afflicted with diabetes, we are now one step closer to a potential cure for the disease.Spring Point Project, a non-profit organization created to expedite the widespread availability of islet tissue for diabetes care, has now conducted the first animal population of its biosecure animal facility in Western Wisconsin to breed and maintain high-health, pathogen-free pigs. [click link for full article]...more >> |
| Scholl's Armstrong In Spain Keynote: 'Amputations Worse Than Cancer' | | Diabetes News From Medical News Today -- 2007-02-27 | | The Spanish National Symposium on the Diabetic Foot last week was the scene for a keynote address that delivered a strong message proposing "a marriage of technology with common sense for the next decade." The address was delivered by David G. Armstrong, DPM, PhD, Professor of Surgery and Associate Dean at Scholl College at Rosalind Franklin University. [click link for full article]...more >> |
| FDA Approvals: RPM, HumaPen Memoir-Luxura HD, Gateway | | Medscape Diabetes Headlines -- 2007-02-27 | The FDA has approved an attachment for a respiratory gating system (RPM), insulin pens with digital memory capability (HumaPen Memoir and Luxura), and a thoracolumbar plate system (Gateway).
Medscape Medical News
Yael Waknine...more >> |
| Garlic Does Not Lower Cholesterol Say Researchers | | Cholesterol News From Medical News Today -- 2007-02-27 | | A new US research study shows that garlic does not lower cholesterol, contrary to popular belief.The study is published in the Archives of Internal Medicine.The scientists, led by Dr Christopher Gardner at the Stanford Prevention Research Center, California, tested raw garlic and two well known garlic supplements in adults with moderately elevated levels of LDL or "bad" cholesterol. [click link for full article]...more >> |
| LifeCycle Pharma Announces Positive Data From LCP-AtorFen Phase I Clinical Program | | Cholesterol News From Medical News Today -- 2007-02-27 | | LifeCycle Pharma A/S (OMX: LCP) announced today positive results from the company's Phase I clinical program with LCP-AtorFen, a fixed-dose combination product of atorvastatin and fenofibrate for the treatment of high cholesterol levels. The program was a comparative pharmacokinetic study between LCP-AtorFen and Lipitor(R) and Tricor(R) and was carried out in Canada. LCP-AtorFen has a convenient single pill once-daily dosing regime and is without food effect. [click link for full article]...more >> |
| Heavily Obese Eight Year Old Boy Could Go Into Care As Last Resort | | Obesity / Weight Loss / Fitness News From Medical News Today -- 2007-02-26 | | An eight-year old boy who weighs 14 stone (196 lbs or 88.9 kilos) could be put into care by his local health authority as a last resort to help him lose weight.Connor McCreaddie, who lives with his mother in Wallsend, North Tyneside, UK is four time as heavy as he should be for his age. An intensive exercise programme and some diet changes have helped him come down by a stone and half (21 lbs, 9. [click link for full article]...more >> |
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