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Wieght loss & maintenance news: diabetes
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We have compiled the list of news articles related to diabetes from online health/medical sources selected based on their reputation and reliability.
| Asia-Pacific Has The Biggest Diabetes Burden In The World | | Diabetes News From Medical News Today -- 2007-03-05 | | Given that in the year 2000 an estimated 83 million people in the Asia-Pacific region were living with type 2 diabetes, representing almost half of the 171 million people with diabetes worldwide, these findings highlight the huge impact that diabetes prevention and awareness campaigns could have in the area. In Australia alone, diabetes is responsible for 4,000 fatal heart attacks and strokes each year. [click link for full article]...more >> |
| Prevalent Rheumatoid Arthritis and Diabetes Among NHANES III Participants Aged 60 and Older | | Endocrinology News -- 2007-03-05 | Journal of Rheumatology
Julia F. Simard, et al. - Conclusion: While this study cannot definitively rule out a modest non-null association, we can conclude that there is no evidence of a strong cross-sectional association between prevalent RA and diabetes in subjects aged >= 60 years. Future longitudinal studies with more participants with RA are required to further evaluate a possible association between RA and the incidence of diabetes...more >> |
| Glycemic and Risk Factor Control in Type 1 Diabetes | | Endocrinology News -- 2007-03-05 | Diabetes Care
Eeg-Olofsson, K., et al. – Are recently updated treatment goals making a difference?<br>><b>Summary: </b> This study investigated the clinical characteristics of a large type 1 diabetic population and to evaluate the degree of fulfillment of recently updated treatment goals. A1C levels, treatment, and risk factors were analyzed in two cross-sectional samples of 9,424 patients in 1997 and 13,612 patients in 2004 and in a smaller longitudinal sample from 1997 to 2004. <br><b>Outcomes: </b>In this large cohort of type 1 diabetic patients, there was a slow improvement in glycemic and risk factor control from 1997 to 2004, although the gap between the clinical results and current Swedish and American treatment goals is still unsatisfactory. It is crucial that additional measures be taken to improve risk factor control in type 1 diabetic patients...more >> |
| Serum Zinc Level and Coronary Heart Disease Events in Patients With Type 2 Diabetes | | Endocrinology News -- 2007-03-05 | Diabetes Care
Soinio, M., et al. – Low serum zinc level a risk factor for CHD events in this diabetic population.<br>><b>Summary: </b> Serum zinc values were obtained from a group of 1,059 patients with type 2 diabetes, aged 45 - 64 years. Mean duration of diabetes was 8 years. CHD mortality and the incidence of nonfatal MI were assessed in a 7-year follow-up.<br><b>Outcomes: </b> Patients with a serum zinc concentration of lower 14.1 µmol/l at baseline had a higher risk for death from CHD than patients with serum zinc level above 14.1 µmol/l. The risks for fatal or nonfatal MI were 30.5 and 22.0%, respectively. A Cox regression analyses determined that low serum zinc concentration was significantly associated with CHD mortality and all CHD events even after adjustment for confounding variables...more >> |
| Effect of Acute Exercise on AMPK Signaling in Skeletal Muscle of Subjects With Type 2 Diabetes | | Endocrinology News -- 2007-03-05 | Diabetes
Apiradee Sriwijitkamol, et al. – Activation of AMP-activated protein kinase (AMPK) by exercise induces several cellular processes in muscle. Exercise activation of AMPK is unaffected in lean (BMI 25 kg/m2) subjects with type 2 diabetes. However, most type 2 diabetic subjects are obese (BMI >30 kg/m2), and exercise stimulation of AMPK is blunted in obese rodents. We examined whether obese type 2 diabetic subjects have impaired exercise stimulation of AMPK, at different signaling levels, spanning from the upstream kinase, LKB1, to the putative AMPK targets...more >> |
| Dipeptidyl peptidase-4 inhibitors and the management of type 2 diabetes mellitus | | Endocrinology News -- 2007-03-05 | Current Opinion in Endocrinology and Diabetes
Rosenstock, Julio, et al. – Long term studies needed to confirm potential of glycemic control.<br>><b>Summary: </b> The purpose of this research was to review recent clinical trials of oral dipeptidyl peptidase-4 inhibitors and examine their role in managing type 2 diabetes mellitus. <br><b>Outcomes: </b>Oral dipeptidyl peptidase-4 inhibitors may prove valuable in the treatment of diabetes, given their effectiveness in reducing glycated hemoglobin with neutral weight effects and without the adverse events associated with other agents. Dipeptidyl peptidase-4 inhibitors appear to improve islet function and may modify the course of diabetes; this, however, must be confirmed with long-term controlled studies to demonstrate sustained glycemic control that translates into [beta]-cell preservation...more >> |
| Diabetes Will Be A Bigger Burden Than Predicted, The Lancet | | Diabetes News From Medical News Today -- 2007-03-02 | | WHO has predicted a 39% rise in the worldwideprevalence of diabetes between 2000 and 2030, butan Article in this week's Lancet indicates that this figuremight be a gross underestimation. Using populationbaseddata from Ontario, Lorraine Lipscombe andcolleagues have observed a 69% increase in theprevalence of known diabetes from 1995 to 2005; anincrease that already exceeds WHO's predicted rate. [click link for full article]...more >> |
| US adults average spending on diabetes treatment increases over 7 years | | Endocrinology News -- 2007-03-02 | Formulary
Between 1996 and 2003, average constant dollar expenditures on prescription medications by adults with >=1 medical event for the treatment of diabetes increased 87.3% in those aged 18 to 44 years, 114.9% in those aged 45 to 64 years, and 61.4% in those aged >=65 years...more >> |
| Patients With Type 1 Diabetes Don't Wake In Response To Hypoglycemia | | Diabetes News From Medical News Today -- 2007-02-28 | | A study of 16 patients with type 1 diabetes mellitus (T1DM) and 16 normal individuals shows that only one of the 16 T1DM patients, as compared to ten healthy control participants, awakened upon hypoglycemia.Bernd Schultes and colleagues from the University of Lubeck induced hypoglycemia with insulin under controlled conditions and then assessed sleep with polysomography. A fall in plasma glucose to 2. [click link for full article]...more >> |
| Growth Hormone To Boost Athletic Performance Risks Diabetes | | Diabetes News From Medical News Today -- 2007-02-28 | | Use of growth hormone to boost athletic performance can lead to diabetes, reports a study published ahead of print in the British Journal of Sports Medicine.The study reports the case of a 36 year old professional body-builder who required emergency care for chest pain.He had lost 40 kg in 12 months, during which he had also experienced excessive urination, thirst, and appetite. [click link for full article]...more >> |
| Journal Scan - Type 2 Diabetes | | Medscape Diabetes Headlines -- 2007-02-28 | The third issue of this special report focuses on A Diabetes Outcome Progression Trial and other studies presented at the International Diabetes Federation World Congress.
(CME)
Medscape Diabetes & Endocrinology
Gregory Nichols...more >> |
| Expert Column - A Diabetes Outcome Progression Trial (ADOPT) | | Medscape Diabetes Headlines -- 2007-02-28 | The third issue of this special report focuses on A Diabetes Outcome Progression Trial and other studies presented at the International Diabetes Federation World Congress.
(CME)
Medscape Diabetes & Endocrinology
Steven Haffner...more >> |
| Type 2 Diabetes: The Latest Research, Volume 3 | | Medscape Diabetes Headlines -- 2007-02-28 | | The third issue of this special report focuses on A Diabetes Outcome Progression Trial and other studies presented at the International Diabetes Federation World Congress. (CME)...more >> |
| One Step Closer To A Potential Cure For Diabetes | | Diabetes News From Medical News Today -- 2007-02-27 | | For the millions of people worldwide who are afflicted with diabetes, we are now one step closer to a potential cure for the disease.Spring Point Project, a non-profit organization created to expedite the widespread availability of islet tissue for diabetes care, has now conducted the first animal population of its biosecure animal facility in Western Wisconsin to breed and maintain high-health, pathogen-free pigs. [click link for full article]...more >> |
| Diabetes Risk Factors Develop Earlier In Women Than Men | | Diabetes News From Medical News Today -- 2007-02-23 | | The "diabetes clock" may start ticking in women years in advance of a medical diagnosis of the disease, new research has shown.Epidemiologists at the University at Buffalo have found that newly identified risk factors for diabetes found in the blood, such as markers of endothelial dysfunction, chronic sub-acute inflammation and blood clotting factors, are present early on in women who eventually progress from normal glucose status to the pre-diabetic condition. [click link for full article]...more >> |
| Research Identifies Risk-Factor Genes For Type 2 Diabetes | | Diabetes News From Medical News Today -- 2007-02-23 | | A new study led by researchers at the McGill University Health Centre (MUHC) has identified four genes that increase the risk of developing type 2 diabetes. This form of diabetes is the most common worldwide and affects nearly 2 million Canadians. In recent years, the prevalence of Type 2 diabetes has increased rapidly. This genetic discovery may help stem this rise.This genetic study, published in the journal Nature, was led by MUHC endocrinologist Dr. [click link for full article]...more >> |
| Study Of Diabetes And Race Reveals The Imperfect Science Of Defining Ethnic Groups | | Diabetes News From Medical News Today -- 2007-02-20 | | While previous biomedical research studies have found that genetics and race increase risk for some diseases, a new look into how researchers study genetic triggers of type 2 diabetes suggests that defining race remains an inexact science, with social and historic facts mixing with biology throughout the research process. [click link for full article]...more >> |
| Cholesterol Linked With Type 2 Diabetes | | Diabetes News From Medical News Today -- 2007-02-19 | | An international team of scientists have discovered a possible link between accumulation of cholesterol and type 2 diabetes.The study was based at Canada's Vancouver Child and Family Research Institute at the University of British Columbia, and is published online in Nature Medicine.Type 2 diabetes is defined by two things. One is insulin resistance, and the other is reduced insulin production. [click link for full article]...more >> |
| Culturally Specific Diabetes Management Helps Low-Income Patients | | Diabetes News From Medical News Today -- 2007-02-19 | | Diabetes case management that takes a patient's specific culture into consideration can help increase life expectancy and decrease the incidence of diabetes-related complications over the patient's lifetime, a new study finds."Better management results in reduced long-term complications, such as blindness, stroke, amputation and nerve damage," said lead researcher Todd Gilmer, Ph.D. [click link for full article]...more >> |
| Mouse Study Reveals Diabetes Secrets | | MedicineNet Diabetes General -- 2007-01-04 | Title: Mouse Study Reveals Diabetes Secrets
Category: Health News
Created: 1/4/2007 2:06:00 AM
Last Editorial Review: 1/4/2007 2:05:50 AM...more >> |
| Diabetes | | MedicineNet Diabetes General -- 2006-12-05 | Title: Diabetes
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 12/5/2006...more >> |
| Diabetes Treatment | | MedicineNet Diabetes General -- 2006-12-05 | Title: Diabetes Treatment
Category: Diseases and Conditions
Created: 12/5/2006
Last Editorial Review: 12/5/2006...more >> |
| Study Confirms That Significant Insulin Dose Errors Can Result When Blood Glucose Meters Are Miscoded | | Diabetes News From Medical News Today -- 2007-03-02 | | When persons with diabetes use miscoded blood glucose meters to determine how much insulin to take, significant errors in insulin dose can result that may potentially lead to short- and long-term health complications, according to findings of a new study just published in the Journal of Diabetes Science and Technology (http://www.journalofdst.org). [click link for full article]...more >> |
| New Blood Glucose Meters, Contour® And Breeze®2, Now Available In Pharmacies Nationwide, USA | | Diabetes News From Medical News Today -- 2007-03-01 | | Bayer Diabetes Care, a division of Bayer HealthCare LLC and a member of the Bayer Group (NYSE: BAY), announced today the availability of the latest advances in their line of blood glucose meters: the new CONTOUR® and BREEZE®2 meters. As an innovator of meters with No Coding™ technology, Bayer's new meters now offer shorter testing times and easier functionality. [click link for full article]...more >> |
| Glucose Intolerance Linked To Cancer Risk In Women | | Diabetes News From Medical News Today -- 2007-02-28 | | High blood glucose levels -- even before they reach the level needed for a diagnosis of diabetes -- may signal an increased risk for cancer in women, according to a new study being published in the March issue of Diabetes Care. The March journal also includes a study that found a link between high levels of persistent organic pollutants (POPs) in a person's bloodstream and insulin resistance, a precursor for type 2 diabetes. [click link for full article]...more >> |
| PKC-Epsilon Links Fat To Insulin Resistance | | Diabetes News From Medical News Today -- 2007-02-27 | | The accumulation of fat in the liver (hepatic steatosis) can result in non-alcoholic fatty liver disease, which is associated with hepatic insulin resistance and type 2 diabetes mellitus. However, the mechanisms by which fat accumulation leads to hepatic insulin resistance have not been well characterized. [click link for full article]...more >> |
| New Device Safeguards Against Medication Errors At Home | | Diabetes News From Medical News Today -- 2007-02-25 | | Patients suffering from chronic illness such as diabetes, congestive heart failure, coronary artery disease, and depression, can take six-to-nine different medications a day - oftentimes more. Skipped doses, misinterpretation or labels, or confusion over what pills to take at what time can be fatal. [click link for full article]...more >> |
| Lilly Introduces World's First Digital Insulin Pen With Memory | | Diabetes News From Medical News Today -- 2007-02-25 | | Eli Lilly and Company today announced the launch of the first insulin pen with memory, HumaPen® MEMOIR™, to help simplify the daily management of diabetes.MEMOIR is designed to meet the needs of people with diabetes who take several shots of mealtime insulin each day. [click link for full article]...more >> |
| CureDM, Inc. Achieves Two Drug Discovery Milestones | | Diabetes News From Medical News Today -- 2007-02-23 | | CureDM, Inc., a biopharmaceutical company working to develop new therapies that prevent, ameliorate, or reverse diabetes, announces its achievement of two preclinical drug discovery milestones. "Meeting these milestones represents significant progress for CureDM," said Loraine V. [click link for full article]...more >> |
| Blood Pressure Heads Down In The Absence Of PPAR-gamma | | Diabetes News From Medical News Today -- 2007-02-21 | | One of the most serious health conditions in the developed world is the metabolic syndrome (MetS), a collection of disorders (such as obesity and insulin resistance) that lead to increased risk of developing type 2 diabetes and heart disease. A protein known as PPAR-gamma has been shown to be affect most aspects of MetS. However, these studies have had to focus on the affects of PPAR-gamma on one aspect of MetS at a time because mice lacking PPAR-gamma in all cells die before birth. [click link for full article]...more >> |
| Elucidation Of The Genome For Diabetics With DNA Chips | | Diabetes News From Medical News Today -- 2007-02-19 | | The genome of patients with type 2 diabetes (DT2) has been elucidated, for the first time, thanks to the use of new DNA chip technologies allowing 400,000 DNA mutations to be studied simultaneously. New genes conferring a predisposition to DT2 have been identified. They include the zinc transporter of pancreatic insulin-secreting cells (ZnT8), which is a potential target for treatment. [click link for full article]...more >> |
| Rosiglitazone (Avandia) Linked to Fractures in Women | | MedPage Today Endocrinology -- 2007-02-21 | | ROCKVILLE, Md. -- The FDA informed physicians today of a report by GlaxoSmithKline of an increased number of arm, hand, and foot fractures among women taking rosiglitazone (Avandia) for newly diagnosed type 2 diabetes....more >> |
| Prediction of Diabetic Nephropathy Using Urine Proteomic Profiling 10 Years Prior to Development of Nephropathy | | Endocrinology News -- 2007-03-05 | Diabetes Care
Hasan H. Otu, PHD., et al. – Is proteomic profiling valuable in identifying progression of diabetic nephropathy?<br>><b>Summary: </b> In a nested case-control study of Pima Indians with type 2 diabetes, baseline and 10-year urine samples were examined. Thirty one case subjects developed diabetic nephropathy over 10 years. The same number of control subjects were matched to case subjects according to diabetes duration, age, sex, and BMI but remained normoalbuminuric over the same 10 years. The study examined whether proteomic technologies could identify novel urine proteins associated with subsequent development of diabetic nephropathy.<br><b>Outcomes: </b>Urine proteomic profiling identifies normoalbuminuric subjects with type 2 diabetes who subsequently develop diabetic nephropathy. Further studies are needed to characterize the specific proteins involved in this early prediction...more >> |
| Superiority of Small Islets in Human Islet Transplantation | | Endocrinology News -- 2007-03-05 | Diabetes
Lehmann, R., et al. – Small islet size is a key factor in transplantation success.<br>><b>Summary: </b> This research assessed insulin secretion of large and small islets and quantified cell death during hypoxic conditions simulating the intraportal transplant environment. In the clinical setting, the influence of transplanted islet size on insulin production in patients with type 1 diabetes was analysed.<br><b>Outcomes: </b> Results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture. Islet size seems to be a key factor determining human islet transplantation outcome...more >> |
| Prospective randomized controlled study of Hydrofiber® dressing containing ionic silver or calcium alginate dressings in non-ischaemic diabetic foot ulcer | | Endocrinology News -- 2007-03-05 | Diabetic Medicine
Jude, E. B, et al. – Are there measurable clinical effects of a primary wound dressing containing silver? <br>><b>Summary: </b> A prospective, multicentre study compared clinical efficacy and safety of AQUACEL® Hydrofiber® dressings containing ionic silver (AQAg) with those of Algosteril® calcium alginate (CA) dressings in managing out-patients with Type 1 or 2 diabetes mellitus and non-ischaemic Wagner Grade 1 or 2 DFUs. <br><b>Outcomes: </b> When added to standard care with appropriate off-loading, AQAg silver dressings were associated with favourable clinical outcomes compared with CA dressings, specifically in ulcer depth reduction and in infected ulcers requiring antibiotic treatment. This study reports the first significant clinical effects of a primary wound dressing containing silver on DFU healing...more >> |
| Thiazolidinediones and vascular damage | | Endocrinology News -- 2007-03-05 | Current Opinion in Endocrinology and Diabetes
Goldberg, Ronald B, - Will use of these drugs prevent cardiovascular disease?<br>><b>Summary: </b>The purpose of this review was to investigate the possibility of thiazolidinedione agents having vasculoprotective effects and if so whether these are associated with the prevention of cardiovascular disease.<br><b>Outcomes: </b>The weight of the experimental, subclinical and clinical assessments of the effects of these agents supports the contention that they are vasculoprotective. In the final analysis their use in clinical practice to prevent cardiovascular disease will mostly depend on whether clinical trials consistently demonstrate that they reduced cardiovascular events...more >> |
| Insulin Secretion and Insulin Sensitivity in Relation to Fasting Glucose in Healthy Subjects | | Endocrinology News -- 2007-03-05 | Diabetes Care
Bo Ahrén, MD, PHD., - Does high, but still normal, fasting glucose contribute to augmented insulin secretion?<br>><b>Summary: </b> A total of 148 healthy 50+ year old women underwent a glucose-dependent arginine stimulation test and a 2-h euglycemic-hyperinsulinemic clamp. In the arginine test, arginine (5 g) was injected intravenously under baseline (fasting) conditions and after raising the glucose levels to 15 and >28 mmol/l. From this test, the acute insulin response (AIR) to arginine during the three glucose levels (AIR1, AIR2, and AIR3) were estimated.<br><b>Outcomes: </b> The researchers concluded that 1) raised fasting glucose augments baseline and maximal arginine-induced insulin secretion in healthy subjects, and 2) this is associated with reduced insulin sensitivity. This suggests that high, but still normal, fasting glucose may contribute to the augmented insulin secretion in subjects with low insulin sensitivity...more >> |
| Prospective Study of Hyperglycemia and Cancer Risk | | Endocrinology News -- 2007-03-05 | Diabetes Care
Pär Stattin, MD, PHD., et al. – Is there an association between abnormal glucose metabolism and the development of cancer?<br>><b>Summary: </b> In the Västerbotten Intervention Project of northern Sweden, fasting and postload plasma glucose concentrations were available for 33,293 women and 31,304 men and 2,478 incident cases of cancer were identified. Relative risk (RR) of cancer for levels of fasting and postload glucose was calculated with the use of Poisson models, with adjustment for age, year of recruitment, fasting time, and smoking status. Repeated measurements 10 years after baseline in almost 10,000 subjects were used.<br><b>Outcomes: </b> Risk of cancer of the pancreas, endometrium, urinary tract, and of malignant melanoma was statistically significantly associated with high fasting glucose. The association of hyperglycemia with total cancer risk in women and in women and men combined for several cancer sites, independently of obesity, provides further evidence for an association between abnormal glucose metabolism and cancer...more >> |
| Asia-Pacific Has The Biggest Diabetes Burden In The World | | Diabetes News From Medical News Today -- 2007-03-05 | | Given that in the year 2000 an estimated 83 million people in the Asia-Pacific region were living with type 2 diabetes, representing almost half of the 171 million people with diabetes worldwide, these findings highlight the huge impact that diabetes prevention and awareness campaigns could have in the area. In Australia alone, diabetes is responsible for 4,000 fatal heart attacks and strokes each year. [click link for full article]...more >> |
| Prevalent Rheumatoid Arthritis and Diabetes Among NHANES III Participants Aged 60 and Older | | Endocrinology News -- 2007-03-05 | Journal of Rheumatology
Julia F. Simard, et al. - Conclusion: While this study cannot definitively rule out a modest non-null association, we can conclude that there is no evidence of a strong cross-sectional association between prevalent RA and diabetes in subjects aged >= 60 years. Future longitudinal studies with more participants with RA are required to further evaluate a possible association between RA and the incidence of diabetes...more >> |
| Glycemic and Risk Factor Control in Type 1 Diabetes | | Endocrinology News -- 2007-03-05 | Diabetes Care
Eeg-Olofsson, K., et al. – Are recently updated treatment goals making a difference?<br>><b>Summary: </b> This study investigated the clinical characteristics of a large type 1 diabetic population and to evaluate the degree of fulfillment of recently updated treatment goals. A1C levels, treatment, and risk factors were analyzed in two cross-sectional samples of 9,424 patients in 1997 and 13,612 patients in 2004 and in a smaller longitudinal sample from 1997 to 2004. <br><b>Outcomes: </b>In this large cohort of type 1 diabetic patients, there was a slow improvement in glycemic and risk factor control from 1997 to 2004, although the gap between the clinical results and current Swedish and American treatment goals is still unsatisfactory. It is crucial that additional measures be taken to improve risk factor control in type 1 diabetic patients...more >> |
| Serum Zinc Level and Coronary Heart Disease Events in Patients With Type 2 Diabetes | | Endocrinology News -- 2007-03-05 | Diabetes Care
Soinio, M., et al. – Low serum zinc level a risk factor for CHD events in this diabetic population.<br>><b>Summary: </b> Serum zinc values were obtained from a group of 1,059 patients with type 2 diabetes, aged 45 - 64 years. Mean duration of diabetes was 8 years. CHD mortality and the incidence of nonfatal MI were assessed in a 7-year follow-up.<br><b>Outcomes: </b> Patients with a serum zinc concentration of lower 14.1 µmol/l at baseline had a higher risk for death from CHD than patients with serum zinc level above 14.1 µmol/l. The risks for fatal or nonfatal MI were 30.5 and 22.0%, respectively. A Cox regression analyses determined that low serum zinc concentration was significantly associated with CHD mortality and all CHD events even after adjustment for confounding variables...more >> |
| Effect of Acute Exercise on AMPK Signaling in Skeletal Muscle of Subjects With Type 2 Diabetes | | Endocrinology News -- 2007-03-05 | Diabetes
Apiradee Sriwijitkamol, et al. – Activation of AMP-activated protein kinase (AMPK) by exercise induces several cellular processes in muscle. Exercise activation of AMPK is unaffected in lean (BMI 25 kg/m2) subjects with type 2 diabetes. However, most type 2 diabetic subjects are obese (BMI >30 kg/m2), and exercise stimulation of AMPK is blunted in obese rodents. We examined whether obese type 2 diabetic subjects have impaired exercise stimulation of AMPK, at different signaling levels, spanning from the upstream kinase, LKB1, to the putative AMPK targets...more >> |
| Dipeptidyl peptidase-4 inhibitors and the management of type 2 diabetes mellitus | | Endocrinology News -- 2007-03-05 | Current Opinion in Endocrinology and Diabetes
Rosenstock, Julio, et al. – Long term studies needed to confirm potential of glycemic control.<br>><b>Summary: </b> The purpose of this research was to review recent clinical trials of oral dipeptidyl peptidase-4 inhibitors and examine their role in managing type 2 diabetes mellitus. <br><b>Outcomes: </b>Oral dipeptidyl peptidase-4 inhibitors may prove valuable in the treatment of diabetes, given their effectiveness in reducing glycated hemoglobin with neutral weight effects and without the adverse events associated with other agents. Dipeptidyl peptidase-4 inhibitors appear to improve islet function and may modify the course of diabetes; this, however, must be confirmed with long-term controlled studies to demonstrate sustained glycemic control that translates into [beta]-cell preservation...more >> |
| Insulin Secretion and Insulin Sensitivity in Relation to Fasting Glucose in Healthy Subjects | | Endocrinology News -- 2007-03-05 | Diabetes Care
Bo Ahrén, MD, PHD., - Does high, but still normal, fasting glucose contribute to augmented insulin secretion?<br>><b>Summary: </b> A total of 148 healthy 50+ year old women underwent a glucose-dependent arginine stimulation test and a 2-h euglycemic-hyperinsulinemic clamp. In the arginine test, arginine (5 g) was injected intravenously under baseline (fasting) conditions and after raising the glucose levels to 15 and >28 mmol/l. From this test, the acute insulin response (AIR) to arginine during the three glucose levels (AIR1, AIR2, and AIR3) were estimated.<br><b>Outcomes: </b> The researchers concluded that 1) raised fasting glucose augments baseline and maximal arginine-induced insulin secretion in healthy subjects, and 2) this is associated with reduced insulin sensitivity. This suggests that high, but still normal, fasting glucose may contribute to the augmented insulin secretion in subjects with low insulin sensitivity...more >> |
| Diabetes Will Be A Bigger Burden Than Predicted, The Lancet | | Diabetes News From Medical News Today -- 2007-03-02 | | WHO has predicted a 39% rise in the worldwideprevalence of diabetes between 2000 and 2030, butan Article in this week's Lancet indicates that this figuremight be a gross underestimation. Using populationbaseddata from Ontario, Lorraine Lipscombe andcolleagues have observed a 69% increase in theprevalence of known diabetes from 1995 to 2005; anincrease that already exceeds WHO's predicted rate. [click link for full article]...more >> |
| Study Confirms That Significant Insulin Dose Errors Can Result When Blood Glucose Meters Are Miscoded | | Diabetes News From Medical News Today -- 2007-03-02 | | When persons with diabetes use miscoded blood glucose meters to determine how much insulin to take, significant errors in insulin dose can result that may potentially lead to short- and long-term health complications, according to findings of a new study just published in the Journal of Diabetes Science and Technology (http://www.journalofdst.org). [click link for full article]...more >> |
| US adults average spending on diabetes treatment increases over 7 years | | Endocrinology News -- 2007-03-02 | Formulary
Between 1996 and 2003, average constant dollar expenditures on prescription medications by adults with >=1 medical event for the treatment of diabetes increased 87.3% in those aged 18 to 44 years, 114.9% in those aged 45 to 64 years, and 61.4% in those aged >=65 years...more >> |
| Chronic testosterone treatment induces selective insulin resistance in subcutaneous adipocytes of women | | Endocrinology News -- 2007-03-02 | Journal of Endocrinology
Corbould, A., - Do androgens influence insulin-mediated glucose metabolism in adipose cells?<br>><b>Summary: </b>Preadipocytes harvested from s.c. adipose tissue of healthy women were differentiated in vitro, then treated with testosterone (T) and/or androgen receptor (AR) antagonists (cyproterone acetate, flutamide) for 48 hours. Maximal insulin-stimulated glucose uptake (insulin 10 nM) and increment following insulin stimulation were significantly impaired in cells treated with T 10 and 100 nmol/l.<br><b>Outcomes: </b> The findings of this study are relevant to understanding the pathogenesis of insulin resistance in hyperandrogenic women...more >> |
| Patients With Type 1 Diabetes Don't Wake In Response To Hypoglycemia | | Diabetes News From Medical News Today -- 2007-02-28 | | A study of 16 patients with type 1 diabetes mellitus (T1DM) and 16 normal individuals shows that only one of the 16 T1DM patients, as compared to ten healthy control participants, awakened upon hypoglycemia.Bernd Schultes and colleagues from the University of Lubeck induced hypoglycemia with insulin under controlled conditions and then assessed sleep with polysomography. A fall in plasma glucose to 2. [click link for full article]...more >> |
| Growth Hormone To Boost Athletic Performance Risks Diabetes | | Diabetes News From Medical News Today -- 2007-02-28 | | Use of growth hormone to boost athletic performance can lead to diabetes, reports a study published ahead of print in the British Journal of Sports Medicine.The study reports the case of a 36 year old professional body-builder who required emergency care for chest pain.He had lost 40 kg in 12 months, during which he had also experienced excessive urination, thirst, and appetite. [click link for full article]...more >> |
| Glucose Intolerance Linked To Cancer Risk In Women | | Diabetes News From Medical News Today -- 2007-02-28 | | High blood glucose levels -- even before they reach the level needed for a diagnosis of diabetes -- may signal an increased risk for cancer in women, according to a new study being published in the March issue of Diabetes Care. The March journal also includes a study that found a link between high levels of persistent organic pollutants (POPs) in a person's bloodstream and insulin resistance, a precursor for type 2 diabetes. [click link for full article]...more >> |
| Journal Scan - Type 2 Diabetes | | Medscape Diabetes Headlines -- 2007-02-28 | The third issue of this special report focuses on A Diabetes Outcome Progression Trial and other studies presented at the International Diabetes Federation World Congress.
(CME)
Medscape Diabetes & Endocrinology
Gregory Nichols...more >> |
| Expert Column - A Diabetes Outcome Progression Trial (ADOPT) | | Medscape Diabetes Headlines -- 2007-02-28 | The third issue of this special report focuses on A Diabetes Outcome Progression Trial and other studies presented at the International Diabetes Federation World Congress.
(CME)
Medscape Diabetes & Endocrinology
Steven Haffner...more >> |
| Type 2 Diabetes: The Latest Research, Volume 3 | | Medscape Diabetes Headlines -- 2007-02-28 | | The third issue of this special report focuses on A Diabetes Outcome Progression Trial and other studies presented at the International Diabetes Federation World Congress. (CME)...more >> |
| PKC-Epsilon Links Fat To Insulin Resistance | | Diabetes News From Medical News Today -- 2007-02-27 | | The accumulation of fat in the liver (hepatic steatosis) can result in non-alcoholic fatty liver disease, which is associated with hepatic insulin resistance and type 2 diabetes mellitus. However, the mechanisms by which fat accumulation leads to hepatic insulin resistance have not been well characterized. [click link for full article]...more >> |
| One Step Closer To A Potential Cure For Diabetes | | Diabetes News From Medical News Today -- 2007-02-27 | | For the millions of people worldwide who are afflicted with diabetes, we are now one step closer to a potential cure for the disease.Spring Point Project, a non-profit organization created to expedite the widespread availability of islet tissue for diabetes care, has now conducted the first animal population of its biosecure animal facility in Western Wisconsin to breed and maintain high-health, pathogen-free pigs. [click link for full article]...more >> |
| Lilly Introduces World's First Digital Insulin Pen With Memory | | Diabetes News From Medical News Today -- 2007-02-25 | | Eli Lilly and Company today announced the launch of the first insulin pen with memory, HumaPen® MEMOIR™, to help simplify the daily management of diabetes.MEMOIR is designed to meet the needs of people with diabetes who take several shots of mealtime insulin each day. [click link for full article]...more >> |
| Diabetes Risk Factors Develop Earlier In Women Than Men | | Diabetes News From Medical News Today -- 2007-02-23 | | The "diabetes clock" may start ticking in women years in advance of a medical diagnosis of the disease, new research has shown.Epidemiologists at the University at Buffalo have found that newly identified risk factors for diabetes found in the blood, such as markers of endothelial dysfunction, chronic sub-acute inflammation and blood clotting factors, are present early on in women who eventually progress from normal glucose status to the pre-diabetic condition. [click link for full article]...more >> |
| Research Identifies Risk-Factor Genes For Type 2 Diabetes | | Diabetes News From Medical News Today -- 2007-02-23 | | A new study led by researchers at the McGill University Health Centre (MUHC) has identified four genes that increase the risk of developing type 2 diabetes. This form of diabetes is the most common worldwide and affects nearly 2 million Canadians. In recent years, the prevalence of Type 2 diabetes has increased rapidly. This genetic discovery may help stem this rise.This genetic study, published in the journal Nature, was led by MUHC endocrinologist Dr. [click link for full article]...more >> |
| Study Of Diabetes And Race Reveals The Imperfect Science Of Defining Ethnic Groups | | Diabetes News From Medical News Today -- 2007-02-20 | | While previous biomedical research studies have found that genetics and race increase risk for some diseases, a new look into how researchers study genetic triggers of type 2 diabetes suggests that defining race remains an inexact science, with social and historic facts mixing with biology throughout the research process. [click link for full article]...more >> |
| Cholesterol Linked With Type 2 Diabetes | | Diabetes News From Medical News Today -- 2007-02-19 | | An international team of scientists have discovered a possible link between accumulation of cholesterol and type 2 diabetes.The study was based at Canada's Vancouver Child and Family Research Institute at the University of British Columbia, and is published online in Nature Medicine.Type 2 diabetes is defined by two things. One is insulin resistance, and the other is reduced insulin production. [click link for full article]...more >> |
| Culturally Specific Diabetes Management Helps Low-Income Patients | | Diabetes News From Medical News Today -- 2007-02-19 | | Diabetes case management that takes a patient's specific culture into consideration can help increase life expectancy and decrease the incidence of diabetes-related complications over the patient's lifetime, a new study finds."Better management results in reduced long-term complications, such as blindness, stroke, amputation and nerve damage," said lead researcher Todd Gilmer, Ph.D. [click link for full article]...more >> |
| Mouse Study Reveals Diabetes Secrets | | MedicineNet Diabetes General -- 2007-01-04 | Title: Mouse Study Reveals Diabetes Secrets
Category: Health News
Created: 1/4/2007 2:06:00 AM
Last Editorial Review: 1/4/2007 2:05:50 AM...more >> |
| Diabetes | | MedicineNet Diabetes General -- 2006-12-05 | Title: Diabetes
Category: Diseases and Conditions
Created: 12/31/1997
Last Editorial Review: 12/5/2006...more >> |
| Diabetes Treatment | | MedicineNet Diabetes General -- 2006-12-05 | Title: Diabetes Treatment
Category: Diseases and Conditions
Created: 12/5/2006
Last Editorial Review: 12/5/2006...more >> |
| New Blood Glucose Meters, Contour® And Breeze®2, Now Available In Pharmacies Nationwide, USA | | Diabetes News From Medical News Today -- 2007-03-01 | | Bayer Diabetes Care, a division of Bayer HealthCare LLC and a member of the Bayer Group (NYSE: BAY), announced today the availability of the latest advances in their line of blood glucose meters: the new CONTOUR® and BREEZE®2 meters. As an innovator of meters with No Coding™ technology, Bayer's new meters now offer shorter testing times and easier functionality. [click link for full article]...more >> |
| New Device Safeguards Against Medication Errors At Home | | Diabetes News From Medical News Today -- 2007-02-25 | | Patients suffering from chronic illness such as diabetes, congestive heart failure, coronary artery disease, and depression, can take six-to-nine different medications a day - oftentimes more. Skipped doses, misinterpretation or labels, or confusion over what pills to take at what time can be fatal. [click link for full article]...more >> |
| CureDM, Inc. Achieves Two Drug Discovery Milestones | | Diabetes News From Medical News Today -- 2007-02-23 | | CureDM, Inc., a biopharmaceutical company working to develop new therapies that prevent, ameliorate, or reverse diabetes, announces its achievement of two preclinical drug discovery milestones. "Meeting these milestones represents significant progress for CureDM," said Loraine V. [click link for full article]...more >> |
| Blood Pressure Heads Down In The Absence Of PPAR-gamma | | Diabetes News From Medical News Today -- 2007-02-21 | | One of the most serious health conditions in the developed world is the metabolic syndrome (MetS), a collection of disorders (such as obesity and insulin resistance) that lead to increased risk of developing type 2 diabetes and heart disease. A protein known as PPAR-gamma has been shown to be affect most aspects of MetS. However, these studies have had to focus on the affects of PPAR-gamma on one aspect of MetS at a time because mice lacking PPAR-gamma in all cells die before birth. [click link for full article]...more >> |
| Blood Pressure Heads Down In The Absence Of PPAR-gamma | | Diabetes News From Medical News Today -- 2007-02-21 | | One of the most serious health conditions in the developed world is the metabolic syndrome (MetS), a collection of disorders (such as obesity and insulin resistance) that lead to increased risk of developing type 2 diabetes and heart disease. A protein known as PPAR-gamma has been shown to be affect most aspects of MetS. However, these studies have had to focus on the affects of PPAR-gamma on one aspect of MetS at a time because mice lacking PPAR-gamma in all cells die before birth. [click link for full article]...more >> |
| Elucidation Of The Genome For Diabetics With DNA Chips | | Diabetes News From Medical News Today -- 2007-02-19 | | The genome of patients with type 2 diabetes (DT2) has been elucidated, for the first time, thanks to the use of new DNA chip technologies allowing 400,000 DNA mutations to be studied simultaneously. New genes conferring a predisposition to DT2 have been identified. They include the zinc transporter of pancreatic insulin-secreting cells (ZnT8), which is a potential target for treatment. [click link for full article]...more >> |
| Elucidation Of The Genome For Diabetics With DNA Chips | | Diabetes News From Medical News Today -- 2007-02-19 | | The genome of patients with type 2 diabetes (DT2) has been elucidated, for the first time, thanks to the use of new DNA chip technologies allowing 400,000 DNA mutations to be studied simultaneously. New genes conferring a predisposition to DT2 have been identified. They include the zinc transporter of pancreatic insulin-secreting cells (ZnT8), which is a potential target for treatment. [click link for full article]...more >> |
| Rosiglitazone (Avandia) Linked to Fractures in Women | | MedPage Today Endocrinology -- 2007-02-21 | | ROCKVILLE, Md. -- The FDA informed physicians today of a report by GlaxoSmithKline of an increased number of arm, hand, and foot fractures among women taking rosiglitazone (Avandia) for newly diagnosed type 2 diabetes....more >> |
| Fatty Liver and the Metabolic Syndrome | | Medscape Diabetes Headlines -- 2007-03-01 | Nonalcoholic fatty liver disease and its subset nonalcoholic steatohepatitis represent the liver manifestations of insulin resistance.
Current opinion in gastroenterology...more >> |
| FDA Approvals: RPM, HumaPen Memoir-Luxura HD, Gateway | | Medscape Diabetes Headlines -- 2007-02-27 | The FDA has approved an attachment for a respiratory gating system (RPM), insulin pens with digital memory capability (HumaPen Memoir and Luxura), and a thoracolumbar plate system (Gateway).
Medscape Medical News
Yael Waknine...more >> |
| Prediction of Diabetic Nephropathy Using Urine Proteomic Profiling 10 Years Prior to Development of Nephropathy | | Endocrinology News -- 2007-03-05 | Diabetes Care
Hasan H. Otu, PHD., et al. – Is proteomic profiling valuable in identifying progression of diabetic nephropathy?<br>><b>Summary: </b> In a nested case-control study of Pima Indians with type 2 diabetes, baseline and 10-year urine samples were examined. Thirty one case subjects developed diabetic nephropathy over 10 years. The same number of control subjects were matched to case subjects according to diabetes duration, age, sex, and BMI but remained normoalbuminuric over the same 10 years. The study examined whether proteomic technologies could identify novel urine proteins associated with subsequent development of diabetic nephropathy.<br><b>Outcomes: </b>Urine proteomic profiling identifies normoalbuminuric subjects with type 2 diabetes who subsequently develop diabetic nephropathy. Further studies are needed to characterize the specific proteins involved in this early prediction...more >> |
| Superiority of Small Islets in Human Islet Transplantation | | Endocrinology News -- 2007-03-05 | Diabetes
Lehmann, R., et al. – Small islet size is a key factor in transplantation success.<br>><b>Summary: </b> This research assessed insulin secretion of large and small islets and quantified cell death during hypoxic conditions simulating the intraportal transplant environment. In the clinical setting, the influence of transplanted islet size on insulin production in patients with type 1 diabetes was analysed.<br><b>Outcomes: </b> Results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture. Islet size seems to be a key factor determining human islet transplantation outcome...more >> |
| Superiority of Small Islets in Human Islet Transplantation | | Endocrinology News -- 2007-03-05 | Diabetes
Lehmann, R., et al. – Small islet size is a key factor in transplantation success.<br>><b>Summary: </b> This research assessed insulin secretion of large and small islets and quantified cell death during hypoxic conditions simulating the intraportal transplant environment. In the clinical setting, the influence of transplanted islet size on insulin production in patients with type 1 diabetes was analysed.<br><b>Outcomes: </b> Results provide evidence that small islets are superior to large islets with regard to in vitro insulin secretion and show a higher survival rate during both normoxic and hypoxic culture. Islet size seems to be a key factor determining human islet transplantation outcome...more >> |
| Prospective randomized controlled study of Hydrofiber® dressing containing ionic silver or calcium alginate dressings in non-ischaemic diabetic foot ulcer | | Endocrinology News -- 2007-03-05 | Diabetic Medicine
Jude, E. B, et al. – Are there measurable clinical effects of a primary wound dressing containing silver? <br>><b>Summary: </b> A prospective, multicentre study compared clinical efficacy and safety of AQUACEL® Hydrofiber® dressings containing ionic silver (AQAg) with those of Algosteril® calcium alginate (CA) dressings in managing out-patients with Type 1 or 2 diabetes mellitus and non-ischaemic Wagner Grade 1 or 2 DFUs. <br><b>Outcomes: </b> When added to standard care with appropriate off-loading, AQAg silver dressings were associated with favourable clinical outcomes compared with CA dressings, specifically in ulcer depth reduction and in infected ulcers requiring antibiotic treatment. This study reports the first significant clinical effects of a primary wound dressing containing silver on DFU healing...more >> |
| Thiazolidinediones and vascular damage | | Endocrinology News -- 2007-03-05 | Current Opinion in Endocrinology and Diabetes
Goldberg, Ronald B, - Will use of these drugs prevent cardiovascular disease?<br>><b>Summary: </b>The purpose of this review was to investigate the possibility of thiazolidinedione agents having vasculoprotective effects and if so whether these are associated with the prevention of cardiovascular disease.<br><b>Outcomes: </b>The weight of the experimental, subclinical and clinical assessments of the effects of these agents supports the contention that they are vasculoprotective. In the final analysis their use in clinical practice to prevent cardiovascular disease will mostly depend on whether clinical trials consistently demonstrate that they reduced cardiovascular events...more >> |
| Prospective Study of Hyperglycemia and Cancer Risk | | Endocrinology News -- 2007-03-05 | Diabetes Care
Pär Stattin, MD, PHD., et al. – Is there an association between abnormal glucose metabolism and the development of cancer?<br>><b>Summary: </b> In the Västerbotten Intervention Project of northern Sweden, fasting and postload plasma glucose concentrations were available for 33,293 women and 31,304 men and 2,478 incident cases of cancer were identified. Relative risk (RR) of cancer for levels of fasting and postload glucose was calculated with the use of Poisson models, with adjustment for age, year of recruitment, fasting time, and smoking status. Repeated measurements 10 years after baseline in almost 10,000 subjects were used.<br><b>Outcomes: </b> Risk of cancer of the pancreas, endometrium, urinary tract, and of malignant melanoma was statistically significantly associated with high fasting glucose. The association of hyperglycemia with total cancer risk in women and in women and men combined for several cancer sites, independently of obesity, provides further evidence for an association between abnormal glucose metabolism and cancer...more >> |
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